2 дня назад
Scientist - Proteomics
80 000 - 95 900$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist - Proteomics (Mass Spectrometry/Proteomics): Designing and executing quantitative proteomics experiments to study proteome-wide cellular responses and targeted protein degradation with an accent on laboratory automation, instrument operations, and workflow development. Focus on integrating robotics and liquid handling, optimizing enrichment and sample preparation pipelines, and analyzing complex datasets with DIA-NN, Spectronaut, Proteome Discoverer, R, and Python.
Location: Boston, Massachusetts, United States; 100% onsite
Salary: $80,000–$95,900 per year
Company
conducts cancer research, patient care, medical education, and public health programs.
What you will do
- Design and execute TMT, DIA, and DDA proteomics experiments with internal and external investigators.
- Develop automated workflows for sample preparation, instrument scheduling, data acquisition, and analysis.
- Operate, calibrate, monitor, and maintain Thermo and Bruker mass spectrometry instrumentation.
- Integrate laboratory robotics and liquid-handling systems into proteomics pipelines.
- Develop and troubleshoot whole-cell proteomics, interactome analysis, and enrichment workflows.
- Analyze proteomics data, support biological interpretation, mentor junior staff, and maintain safety, quality-control, and data-integrity standards.
Requirements
- Ph.D. in biochemistry, analytical chemistry, bioengineering, or a related field.
- Strong expertise in mass spectrometry-based proteomics and data analysis.
- Required hands-on experience operating Thermo and/or Bruker mass spectrometers.
- Experience with laboratory automation, robotics, or pipeline development, including Hamilton, Opentrons, or custom workflow scripting.
- Proficiency with quantitative proteomics, including label-free, TMT, DIA, and enrichment techniques.
- Experience with DIA-NN, Proteome Discoverer, R, and Python, plus strong troubleshooting, organizational, and communication skills.
Culture & Benefits
- Collaborative work with cancer biology researchers and interdisciplinary teams.
- Contribution to targeted protein degradation research and emerging therapeutic strategies.
- Access to advanced timsTOF HT, timsTOF Ultra2, and Orbitrap Eclipse Tribrid mass spectrometers.
- Inclusive, diverse, and equitable research and care environment.
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