Senior Research Technician (Mass Spectrometry Proteomics)

Location: Boston, Massachusetts, United States; 100% onsite

Salary: $52,400–$57,200 per year

Company

hirify.global conducts cancer research, patient care, medical education, and public health programs in partnership with Harvard Medical School-affiliated hospitals.

What you will do

• Perform cell culture and drug treatment experiments.
• Prepare proteomics samples through cell lysis, digestion, peptide cleanup, and TMT labeling.
• Run samples on LC-MS systems, including Orbitrap and timsTOF instruments.
• Conduct routine quality control checks and support instrument maintenance under supervision.
• Maintain laboratory notebooks and sample metadata while collaborating with core users on sample processing.
• Implement improved protocols, train junior staff, and support laboratory operations, supplies, and vendor communication.

Requirements

• Bachelor’s degree in biology, chemistry, or a related field.
• 1–4 years of experience in a mass spectrometry or molecular biology laboratory.
• Experience operating Thermo and/or Bruker mass spectrometers is required.
• Experience with mass spectrometry data analysis and quantitative methods.
• Strong attention to detail and ability to follow standard operating procedures.
• Must work onsite in Boston, Massachusetts.

Nice to have

• Experience with mammalian cell culture and proteomics sample preparation.
• Knowledge of statistical and computational methods and R programming.
• Experience with Proteome Discoverer, DIA-NN, or Spectronaut.

Culture & Benefits

• Work in an inclusive, diverse, and equitable research and patient-care environment.
• Contribute to cancer research focused on targeted protein degradation as a therapeutic modality.
• Collaborate with technicians, scientists, postdocs, students, and core users.
• Support a clean and safe laboratory environment.