10 часов назад
Postdoc Oral Lipid-Based Formulations
60 000 - 96 255€
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Postdoc Oral Lipid-Based Formulations (Pharmaceutical Sciences): Developing advanced in vitro characterization methods and next-generation lipid-based formulations for oral delivery of beyond-rule-of-five drug candidates with an accent on dissolution, lipolysis, permeation, and formulation behavior. Focus on building high-throughput screening workflows, connecting formulation performance to drug delivery potential, and supporting in vivo translation through pharmacokinetic and lymphatic transport studies.
Location: On-site in Beerse, Antwerp, Belgium
Salary: €60,000–€96,255 gross annual base pay
Company
Johnson & Johnson MedTech develops healthcare innovations and solutions across the spectrum of medicine and medical technology.
What you will do
- Develop an advanced in vitro characterization toolbox for lipid-based formulations, combining dissolution, lipolysis, precipitation or crystallization, mucus penetration, and permeation readouts.
- Assess downscaling and high-throughput approaches for lipolysis and dissolution-permeation workflows.
- Design and optimize lipid formulation strategies for oral delivery of beyond-rule-of-five drug candidates.
- Support in vivo translation through rat pharmacokinetic, lymphatic transport, and mechanistic studies.
- Present scientific outcomes internally and at scientific forums, and contribute to manuscripts and publication strategy within IP guidelines.
Requirements
- PhD or near completion in Pharmaceutical Sciences, Chemical Engineering, Chemistry, Bioengineering, or a closely related discipline.
- Independent experience designing and executing experimental research, including literature review, planning, laboratory work, data analysis, and reporting.
- Experience with lipid-based formulations and/or biopharmaceutics tools connecting formulation behavior with delivery potential.
- Strong written and verbal English communication skills and scientific output such as publications, presentations, or patents.
- Willingness to work on-site in Beerse, Belgium with hands-on laboratory activities.
Nice to have
- Experience with lipolysis or digestion models, dissolution-permeation methods, PAMPA variants, mucus assays, precipitation or crystallization analytics, or phase characterization.
- Familiarity with lipid-based formulation optimization and in-silico tools such as COSMO.
- Exposure to translational modeling, PBPK or PK, oral absorption, or lymphatic transport studies.
Culture & Benefits
- Two-year postdoctoral assignment in a highly collaborative research environment.
- Annual bonus based on pay grade, location, and individual and company performance.
- Vacation days, parental leave of at least 12 weeks, bereavement leave, caregiver leave, and volunteer leave.
- Well-being reimbursement and programs supporting financial, physical, and mental health.
- Recognition awards and participation in applicable insurance plans.
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