Process Development Senior Principal Scientist (ADC)

Location: Thousand Oaks, California, United States; travel domestically and internationally up to 10% of the time.

Annual salary: USD 157,737.05–213,408.95.

Company

hirify.global is a biotechnology company developing, manufacturing, and delivering medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.

What you will do

• Lead laboratory studies for drug product design, formulation, process development, documentation, and technology transfer.
• Develop and characterize liquid and lyophilized biologic formulations, with emphasis on ADC drug products, handling, and sterile filling.
• Integrate formulation, analytical, stability, and process data to guide product design and commercialization.
• Lead technology transfers with internal teams and CMOs/CDMOs, including process-fit assessments and manufacturing troubleshooting.
• Apply AI, machine learning, and data science to predictive modeling, workflow acceleration, and decision-making.
• Lead matrixed drug product teams and manage engineers and scientists supporting commercialization and lifecycle management.

Requirements

• PhD, PharmD, or MD with 2 years of scientific experience; or a master’s degree with 5 years; or a bachelor’s degree with 7 years.
• Advanced degree in engineering, pharmaceutics, biotechnology, material science, or a related field.
• At least 8 years of experience in pharmaceuticals or biotechnology, including formulation, fill/finish process development, process characterization, technology transfer, and design of experiments.
• Experience with biologic formulation development, stability testing, aseptic processing, manufacturing, regulatory authoring, and agency engagement; direct ADC formulation experience is strongly preferred.
• Knowledge of ADC development, including linker-payload stability, drug-to-antibody ratio, degradation pathways, quality attributes, comparability, and analytical techniques such as UPLC/HPLC, SEC, IEX, RP-HPLC, HIC, and CE-SDS.
• Programming and data skills in Python, R, or MATLAB; SQL; data visualization tools; and statistical software such as SAS, JMP, or Minitab.

Culture & Benefits

• Collaborative, innovative, science-based work environment.
• Comprehensive medical, dental, vision, life, disability, and flexible spending benefits.
• Retirement and savings plan with company contributions.
• Annual bonus program and stock-based long-term incentives.
• Paid time-off plans and career development opportunities.
• Flexible work models where applicable to the posted work location.

Hiring process

• Applications are accepted until a sufficient number of candidates are received or a candidate is selected.
• Sponsorship for the role is not guaranteed.