Scientist, Immunogenicity, Bioanalytical and Molecular Assays (mRNA)

Location: Oxford, England; site-based at hirify.global's Harwell site with full-time onsite presence required and no remote working

Company

hirify.global develops mRNA-based medicines and therapeutics through its proprietary mRNA technology platform.

What you will do

• Design and execute phase-appropriate bioanalytical strategies for regulated clinical programmes.
• Lead development of immunogenicity assays, including anti-drug antibody and neutralising antibody assays, alongside PK and PD assays.
• Develop, optimise, qualify, and validate assays using ELISA, MSD, cell culture, immunoblotting, and related technologies.
• Expand internal bioanalytical capabilities, including laboratory equipment, SOPs, critical reagents, and assay controls.
• Partner with preclinical, clinical operations, and sample management teams on sample journeys and laboratory manuals.
• Troubleshoot technical issues and communicate scientific findings across multidisciplinary global teams.

Requirements

• PhD with at least three years of relevant experience, or MSc with five or more years of hands-on experience in bioanalytical method development, validation, and sample analysis.
• Expertise in electrochemiluminescence, immunoassays, cell culture-based assays, and clinical assay methodologies.
• Strong knowledge of GCP requirements, regulatory expectations, FDA and MHRA standards, and global regulatory data standards.
• Experience with RNA therapeutics, biologics, or cell therapies is preferred; knowledge of translational science and the mRNA field is valuable.
• Ability to manage multiple projects, troubleshoot scientific problems, and communicate technical concepts across multidisciplinary teams.
• Full-time presence at the Harwell site is required; the position is not eligible for remote working.

Nice to have

• Hands-on experience with cell culture assays.
• Experience using LIMS and electronic laboratory notebook platforms.
• Experience with RNA therapeutics, biologics, or cell therapies.

Culture & Benefits

• Collaborative, multidisciplinary environment focused on advancing mRNA science and clinical development.
• Competitive healthcare and voluntary benefit programmes.
• Fitness, mindfulness, and mental health support.
• Family-building benefits, including fertility, adoption, and surrogacy support.
• Paid vacation, bank holidays, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
• Savings and investment programmes, plus location-specific benefits.