Senior Director, Project Management (Oncology)

Location: South San Francisco, California, United States; onsite four days per week. The role includes limited work-from-home flexibility, but employees must work onsite in company facilities for training and meetings.

Salary: $255,000–$315,000 per year.

Company

hirify.global is a precision medicine biotechnology company developing targeted therapies for genetically defined solid tumors, including small-molecule therapies and antibody-drug conjugates.

What you will do

• Lead the IDE892 development program and define program strategy with Clinical and Research leadership.
• Integrate scientific, clinical, regulatory, and commercial inputs into development plans and the Target Product Profile.
• Manage program timelines, critical paths, milestones, budgets, resource alignment, and risk registers.
• Lead cross-functional program teams and coordinate study execution across IDE892-001 cohorts, including RAS combination arms and PDAC and NSCLC expansion.
• Manage the Roche collaboration, including joint program teams, data sharing, governance meetings, and Joint Steering Committee preparation.
• Coordinate readiness for regulatory interactions, IND amendments, data readouts, and potential registrational development.

Requirements

• PhD in biology, pharmacology, biochemistry, or a related life sciences discipline.
• At least 10 years of pharmaceutical or biotechnology drug development experience, including at least 5 years in program management.
• Experience leading cross-functional oncology teams through Phase 1 and Phase 2 development.
• Strong oncology scientific fluency, with experience in RAS-driven cancers or MTAP, EGFR, or KRAS biology.
• Experience managing integrated plans, budgets, risks, external partnerships, and late-phase or registrational submissions such as BLA, NDA, or sNDA.
• PMP certification or equivalent program management training; experience in a lean, clinical-stage biotech environment is required.

Nice to have

• Experience with combination oncology development strategy and contribution-of-components frameworks.

Culture & Benefits

• Collaborative, inclusive, data-driven environment focused on precision oncology and improving outcomes for cancer patients.
• Medical, dental, and vision coverage, with 100% employee and 90% dependent coverage.
• 401(k), employee stock purchase plan, wellness programs, merit-based salary increases, incentive plan participation, and potential stock options.
• Employees working in company facilities must be fully vaccinated against COVID-19, subject to applicable accommodations.