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1 день назад

Computational Biologist (Cellularization)

127 500 - 150 000$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Computational Biologist (Cellularization) (Computational Biology/Cellular Modeling): Building multiscale computational models of lung cellularization in 3D-printed scaffolds with an accent on cell division, migration, adhesion, and mechanistic simulation. Focus on integrating cell-based models into organ-to-molecular simulations, qualifying model uncertainty, and guiding experimental design for manufactured organs and regenerative medicine.

Location: Silver Spring, Maryland, United States; based on the Silver Spring campus at least 4 days per week

Salary: $127,500–$150,000 per year

Company

hirify.global is a public benefit biotech and pharmaceutical company developing therapies for rare diseases and technologies for manufactured, transplantable organs.

What you will do

  • Develop mathematical models of lung cellular processes, including cell division, migration, and adhesion, in 3D-printed scaffolds.
  • Use mechanistic modeling and simulation to analyze cellularization experiments with endothelial, epithelial, and other cell types.
  • Design iterative experiments based on model-generated hypotheses and evaluate uncertainty and variability in model outputs.
  • Integrate cell-based models into multiscale lung models spanning molecular, cellular, and organ-level processes.
  • Collaborate with internal and external laboratories to generate data for model training and validation.
  • Communicate findings through visualizations, presentations, and peer-reviewed publications.

Requirements

  • Master’s degree in biomedical engineering, computational biology, applied mathematics, or a related field with 6+ years of industry experience developing computational models of biological systems, or a PhD with 2+ years of relevant industry experience.
  • Expertise in cell-level modeling frameworks such as agent-based models or cellular Potts models.
  • Experience with numerical methods, including ordinary and partial differential equations, optimization, and Monte Carlo methods.
  • Fluency in a scientific programming language such as Python, R, or Julia.
  • Experience with cell-based modeling and simulation packages such as Morpheus or CompuCell3D.
  • Knowledge of molecular and cellular biology, drug development, and effective communication with technical and non-technical audiences.

Nice to have

  • PhD in biomedical engineering, computational biology, applied mathematics, or a related field.
  • Familiarity with quantitative systems pharmacology and modeling applications in pharmaceutical drug discovery and development.
  • Experience with statistical and machine learning methods.
  • Knowledge of pulmonary physiology.

Culture & Benefits

  • Medical, dental, vision, and prescription coverage.
  • Wellness resources, 401(k), and employee stock purchase plan.
  • Paid time off and paid parental leave.
  • Disability benefits and additional employee programs.

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