Associate Director/Director (Clinical Pharmacology)

Location: Remote - US; San Diego headquarters

Salary: Associate Director $164K–$205K; Director $196K–$245K per year

Company

hirify.global is a clinical-stage life-science and technology company developing medicines through an AI-driven discovery and development platform.

What you will do

• Design and execute clinical pharmacology strategies for oncology small-molecule programs from IND-enabling activities through Phase 1 and later development.
• Analyze and interpret clinical PK, PK/PD, and exposure-response data across multidisciplinary development teams.
• Design first-in-human, drug-drug interaction, hepatic and renal impairment, food-effect, cardiac safety, and combination-therapy studies.
• Apply PBPK, population PK, and exposure-response modeling to support dose selection and DDI risk assessment.
• Author and review protocols, investigator brochures, SOPs, statistical analysis plans, clinical study reports, regulatory submissions, and responses to health authority queries.
• Contribute to scientific publications and mentor junior scientists within the clinical pharmacology function.

Requirements

• PhD or equivalent in pharmacology, biomedicine, biochemistry, or a related scientific discipline, with at least 5 years of relevant pharmaceutical, contract research, or clinical research experience.
• Experience with clinical development of oncology small-molecule therapeutics, including dose-escalation, dose-expansion, and combination-therapy trials.
• Proficiency with Phoenix WinNonlin for non-compartmental analysis.
• Working knowledge of PBPK modeling, ICH M12, FDA DDI guidance, and related regulatory frameworks.
• Hands-on experience writing clinical and regulatory documentation, plus strong project management and cross-functional communication skills.

Nice to have

• Familiarity with PK bioanalytical method development and validation.

Culture & Benefits

• Inclusive environment focused on collaboration, diversity, and teamwork.
• Company-paid healthcare, flexible spending accounts, voluntary life insurance, and 401(k) matching.
• Uncapped vacation.
• San Diego facility with an onsite gym and dining.