Principal Statistical Programmer (SAS)

Location: Boston, MA, United States. The role is remote-eligible, with remote, hybrid, or on-site work arrangements available under the company flex program.

Salary: $149,200–$223,800 annually, plus eligibility for an annual bonus and equity awards.

Company

Vertex is a global biotechnology company focused on scientific innovation.

What you will do

• Lead statistical programming activities for clinical sub-teams and delegate work while tracking progress.
• Develop and use advanced SAS programs, including SAS Macro, BASE SAS, SAS/STAT, and SAS/GRAPH.
• Perform quality control of SAS code and outputs produced by other Statistical Programmers.
• Solve complex clinical trial reporting problems and support accurate, timely study execution.
• Create analyses, files, and documentation for electronic submissions in eCTD format, including ISS and ISE.
• Coordinate with Statistical Programming, Biostatistics, Data Management, and other submission-related functions on reporting, process improvement, and technology initiatives.

Requirements

• Bachelor’s degree in a scientific discipline.
• Typically 8+ years of experience with a bachelor’s degree, or 5+ years with an M.S. or higher, in biotechnology, pharmaceuticals, or a clinical research organization.
• Strong proficiency in SAS programming, procedures, and functions used in clinical trial reporting.
• Intermediate knowledge of CDISC standards and clinical trials.
• Experience with regulatory submissions and FDA/ICH/GCP compliance.
• Effective written and verbal communication skills for explaining complex information.

Culture & Benefits

• Choice of remote, hybrid, or on-site work under the Flex @ Vertex program.
• Medical, dental, and vision benefits.
• Generous paid time off, including week-long summer and winter company shutdowns.
• Educational assistance programs, including student loan repayment.
• Commuting subsidy, matching charitable donations, and 401(k).