Senior Development Scientist I (NGS)

Location: Onsite in Brisbane, California, United States

Company

hirify.global develops multiomic clinical technologies designed to detect cancer earlier.

What you will do

• Develop, optimize, characterize, verify, and validate clinical-grade NGS assays for DNA, including genome-wide and targeted approaches.
• Lead experimental strategy, design, planning, execution, timelines, data analysis, documentation, and scientific presentations.
• Troubleshoot complex technical challenges, identify root causes, and improve assay performance and laboratory workflows.
• Plan projects, define milestones, mitigate risks, and adapt priorities to evolving program needs.
• Collaborate with computational scientists, engineers, and clinical laboratory teams to transfer protocols into automated, high-throughput clinical production.
• Document product development requirements and author study protocols, reports, and SOPs in accordance with cGLP and cGDP.

Requirements

• PhD in molecular biology, biochemistry, genetics, or a related field with at least 4 years of life-sciences experience, or a bachelor's or master's degree with at least 10 years of professional experience.
• Experience designing and leading verification and validation studies for IVD assays in a regulated clinical laboratory environment.
• Extensive hands-on experience developing automated NGS assays, including extraction, library preparation, target capture, sequencing, automated platforms, and liquid handlers.
• Experience with nucleic-acid extraction and purification, amplification, quantification, PCR, qPCR, Qubit, Fragment Analyzer, TapeStation, and ctDNA/cfDNA workflows.
• Ability to independently design and execute experiments, analyze data, present scientific results, troubleshoot investigations, and maintain detailed records.
• Strong written and verbal communication, cross-functional collaboration, adaptability, and experience mentoring scientists and research associates.

Nice to have

• Experience working with methylated ctDNA/cfDNA in NGS workflows.
• Familiarity with Python or R and experience contributing to publications, patents, or other scientific innovations.

Culture & Benefits

• Equity and cash bonus eligibility.
• Medical, financial, and other benefits based on the position offered.
• Multidisciplinary collaboration focused on technical excellence and continuous improvement.
• Equal-opportunity workplace that values diversity.