Postdoctoral Fellow (Protein Sciences)

Location: South San Francisco, California, United States of America

Salary: $100,000–$106,500 per year

Company

hirify.global is a biotechnology company within the Roche Group that discovers and develops medicines for serious and life-threatening diseases.

What you will do

• Investigate fundamental questions in membrane protein biology.
• Study the structural and functional mechanisms of transmembrane proteins and endogenous macromolecular signaling complexes.
• Apply cryo-EM, endogenous purification, and functional reconstitution approaches in recombinant and endogenous systems.
• Design, execute, and troubleshoot complex biochemical and structural biology workflows.
• Collaborate with hirify.global and academic laboratories and present research at conferences.

Requirements

• Ph.D. in structural biology, biochemistry, biophysics, or a related field.
• First-author publication record in high-impact journals.
• Required experience expressing and purifying challenging proteins.
• Required experience preparing samples, collecting data, and processing data for single-particle cryo-EM and/or X-ray crystallography.
• Ability to work independently and communicate effectively in writing and orally.
• Strong collaborative skills for advancing research projects.

Nice to have

• Experience expressing and purifying membrane proteins.
• Experience reconstituting membrane proteins in liposomes or nanodiscs and establishing functional transport or signaling assays.
• Experience isolating endogenous complexes from tissues or cell lines.
• Experience with mammalian cell culture, heterologous expression, or cellular functional assays.

Culture & Benefits

• Access to state-of-the-art structural biology and biophysical equipment and facilities.
• Opportunities for collaboration across hirify.global and with academic laboratories.
• Fully funded research expenses through the postdoctoral program.
• Mentorship, scientific seminars, professional development workshops, and networking opportunities.
• Relocation benefits are available.