Director, Clinical Pharmacology (Pharmacometric Modeling)

Location: New York, New York or Salt Lake City, Utah preferred; remote work is considered for U.S. locations with regular on-site visits required.

Salary: $212,900–$297,000 annual base salary, plus annual bonus and equity compensation.

Company

hirify.global is a clinical-stage TechBio company developing investigational medicines through an AI-native drug discovery and development platform.

What you will do

• Lead clinical pharmacology and pharmacometric strategies for rare disease and oncology clinical programs.
• Provide clinical pharmacology input across Phase 1–3 studies and design dedicated clinical pharmacology studies.
• Author clinical pharmacology sections for Investigator’s Brochures, INDs, NDAs, and other regulatory submissions.
• Represent clinical pharmacology in interactions with regulatory health authorities.
• Collaborate with clinical, translational, preclinical, DMPK, toxicology, biomarker, regulatory, and biostatistics teams.
• Oversee or perform modeling and simulation to support dose selection, exposure-response, and exposure-safety decisions.

Requirements

• Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related discipline; M.D. with clinical pharmacology expertise; or Pharm.D. with a clinical pharmacology fellowship.
• 5–9+ years of experience in biotechnology or pharmaceutical drug development.
• Demonstrated success leading clinical pharmacology aspects of drug development.
• Experience with PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations.
• Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software.
• Experience responding to regulatory agency questions, preparing regulatory submissions, and attending regulatory meetings.

Nice to have

• Oncology experience.

Culture & Benefits

• Cross-functional collaboration across discovery and development sciences.
• Values centered on integrity, ownership, direct communication, adaptability, and urgency for patients.
• Remote work option with regular on-site visits for routine work and departmental events.
• Annual bonus, equity compensation, and comprehensive benefits.
• Equal opportunity workplace with accommodations available during the selection process.