Postdoctoral Fellow (Imaging Technology and Compound Screening)

TL;DR

Postdoctoral Fellow (Imaging Technology & AI): Developing high-throughput imaging platforms to reveal compound effects across model systems with an accent on experimental and computational method development. Focus on designing high-plex assays, applying machine learning to image analysis, and executing large-scale screens to accelerate drug discovery.

Location: Must be based in or be able to relocate to South San Francisco, California, USA

Salary: $100,000 – $106,500

Company

hirify.global, a member of the Roche group, is a pioneer in the biotechnology industry dedicated to discovering and developing medicines for serious and life-threatening diseases.

What you will do

• Develop and optimize high-plex imaging assays that capture multiplexed readouts of cell state and morphology.
• Create computational approaches to expand information extraction and improve imaging-based measurement quality.
• Design and execute large-scale compound screens across diverse, disease-relevant model systems.
• Apply single-cell and multi-omics analyses to build maps of perturbation relationships and prioritize compounds.
• Leverage laboratory automation and high-throughput workflows to iteratively design and run screens at scale.
• Collaborate with cross-disciplinary scientists and contribute to high-impact scientific publications.

Requirements

• Ph.D. in single-cell genomics, imaging, bioengineering, biophysics, quantitative biology, or a related field.
• Proven track record of excellence with at least one first-author paper in a leading peer-reviewed journal.
• Strong hands-on experience in microscopy and quantitative imaging.
• Computational expertise in image analysis and machine learning.
• Fluency in programming with Python or a comparable language.
• Ability to work onsite in South San Francisco, CA.

Nice to have

• Experience developing or deploying multiplexed imaging assays.
• Experience with AI/ML applied to imaging or high-dimensional biological data.
• Knowledge of laboratory automation, liquid handling, and high-throughput workflows.
• Experience analyzing large-scale perturbation datasets and integrating multimodal data.

Culture & Benefits

• Competitive salaries and fully funded research expenses.
• Access to world-class seminars, professional development workshops, and networking opportunities.
• Mentorship and support to transition into an independent scientist and leader.
• Opportunity to conduct world-class research and publish in top-tier journals.
• Relocation benefits are available for this position.