Manager, CMO Operations, VMT Lead (Autologous CAR-T)

TL;DR

Manager, CMO Operations, VMT Lead (Biotech): Managing end-to-end operational oversight of Contract Manufacturing Organizations (CMOs) for the commercial manufacture of autologous CAR-T cell therapies with an accent on performance management, supply reliability, and risk oversight. Focus on driving operational excellence, managing KPIs, and ensuring compliant, on-time delivery of patient-specific drug products.

Location: Hybrid, Raritan, New Jersey, United States

Salary: $110,706 - $145,303 USD

Company

Global biotechnology company dedicated to developing advanced cell therapies to treat and cure life-threatening diseases.

What you will do

• Oversee end-to-end operational execution at CMOs from apheresis through final drug product release and shipment.
• Lead the Value Management Team (VMT) to drive performance using KPIs and structured governance processes.
• Proactively identify and mitigate operational, capacity, and compliance risks to protect patient supply.
• Drive continuous improvement initiatives at CMO sites to enhance reliability, cycle time, and yield.
• Collaborate with internal Quality, MSAT, Planning, and Supply Chain teams to ensure commercial commitments.
• Lead routine business reviews and escalation forums with external manufacturing partners.

Requirements

• Bachelor’s degree or higher in engineering, biological sciences, pharmaceutical sciences, or a related technical discipline.
• Minimum 5 years of industry experience in biologics CMC development or commercial manufacturing.
• Hands-on experience managing CMOs and/or CROs in a regulated GMP environment.
• Must be based in or able to work in Raritan, NJ.
• Strong understanding of deviation management and supply risk management.
• Proven ability to lead through influence in a matrixed, cross-functional organization.

Culture & Benefits

• Medical, dental, and vision insurance.
• 401(k) retirement plan with a company match that vests fully on day one.
• Eight weeks of paid parental leave after three months of employment.
• Comprehensive PTO policy including vacation, personal, and sick time.
• Flexible spending and health savings accounts.
• Life and AD&D insurance, as well as short- and long-term disability coverage.