Senior Research Associate, Antibody Display (Biotech)

TL;DR

Senior Research Associate, Antibody Display (Biotech): Developing and executing display workflows to determine the binding, stability, and function of antibodies and biologics with an accent on high-dimensional datasets and automation. Focus on optimizing assays for precision and speed, utilizing MACS/FACS, and building platforms for closed-loop autonomous science.

Location: Cambridge, MA USA

Salary: $80,000 - $102,000 USD

Company

hirify.global is building Scientific Superintelligence™ to accelerate discovery across medicine, materials, and energy using an autonomous AI Science Factory™.

What you will do

• Develop in vitro and in vivo display workflows to determine the binding, stability, and function of antibodies and other biologics.
• Implement display workflows to generate novel high-dimensional datasets that advance scientific super intelligence.
• Partner with protein design and automation teams to create highly precise and complex protein design libraries.
• Utilize MACS and FACS for the selection of biologics with desired properties.
• Design and execute platforms for automated, high-throughput experimentation and data-rich workflows.
• Collaborate with cross-functional scientists to document systems and refine best practices in autonomous science.

Requirements

• MSc in Molecular Biology/Biotechnology with 1+ year of experience, or BSc with 3+ years, in antibody or peptide development using display-based methods.
• Expertise in pooled display assays and antibody selection using yeast or in vitro (mRNA/ribosome/cDNA) display techniques.
• Proficiency in molecular biology: PCR, NGS library construction, in vitro transcription/translation, and bead-based selections.
• Experience with flow cytometry and sorting yeast using FACS.
• Experience with the analysis of NGS sequencing data supporting display campaigns.
• Must be based in Cambridge, MA USA

Nice to have

• Experience operating Illumina sequencers.
• Experience with laboratory automation.
• Experience with single cell or in situ sequencing.

Culture & Benefits

• Competitive base compensation with bonus potential.
• Generous early-stage equity.
• Comprehensive U.S. and International benefits.
• Fast-paced startup environment focused on solving historic global challenges.