Computational Associate II (Bioinformatics)

TL;DR

Computational Associate II (Bioinformatics): Developing novel liquid biopsy assays for cancer detection and monitoring based on circulating tumor DNA (ctDNA) with an accent on implementing and optimizing bioinformatics workflows. Focus on applying novel diagnostic assays to clinical studies and improving the predictive and prognostic power of cancer detection algorithms.

Location: On-Site in Cambridge, MA

Salary: $58,000 – $80,667 per year

Company

The hirify.global of MIT and Harvard is a leading research organization focused on developing genomic medicine and cancer diagnostics.

What you will do

• Implement, optimize, and apply novel bioinformatics methods for cancer detection and monitoring.
• Collaborate with lab members to design, conduct, analyze, and troubleshoot experiments.
• Perform analyses that directly inform new experiments and the application of diagnostic assays to clinical studies.
• Present project updates and discuss new ideas routinely at lab meetings.
• Assist in the preparation of manuscripts to report findings to the scientific community.

Requirements

• B.S. in Bioinformatics, Computational Biology, Computer Science, or related field with 2+ years of experience, or an M.S. degree.
• Proficiency in R or Python.
• Practical experience with Unix/Linux environments.
• Must be based in or able to work on-site in Cambridge, MA.
• Excellent communication and interpersonal skills.

Nice to have

• Experience with WDL/Cromwell or Snakemake workflow management systems.
• Experience with cloud computing platforms such as Google Cloud Platform (GCP).
• Familiarity with DNA sequencing and molecular biology.
• Experience with epigenetic sequencing methods (bisulfite, EM-Seq, TAPS).
• Experience with Duplex Sequencing and cell-free RNA sequencing.
• Experience developing and validating cancer detection algorithms.

Culture & Benefits

• Comprehensive benefits package including medical, dental, vision, life, and disability insurance.
• 401(k) retirement plan.
• Flexible spending and health savings accounts.
• Generous paid time off, including at least 13 paid holidays and winter closure.
• Parental and family care leave.
• Access to a multidisciplinary team of scientists, engineers, and medical oncologists from MIT and Harvard.