Scientist I/II, Drug Delivery Chemistry (AI)

TL;DR

Scientist I/II, Drug Delivery Chemistry (AI): Designing and developing a high-throughput chemical synthesis platform for drug delivery applications with an accent on medicinal chemistry and structure-activity relationships. Focus on synthesizing novel lipids and small molecules, deploying automated assay platforms, and implementing AI-driven experimental design for closed-loop optimization.

Location: Onsite in Cambridge, MA, USA

Salary: $108,000 - $170,000 USD

Company

hirify.global is building Scientific Superintelligence™ to accelerate discovery across medicine, materials, and energy using autonomous AI Science Factory™ instruments.

What you will do

• Design, synthesize, and optimize novel lipids and small molecule libraries for drug delivery applications.
• Deploy high-throughput synthesis strategies and build automated assay platforms to interrogate large chemical spaces.
• Partner with computational and automation teams to establish structure-activity relationships for compound libraries.
• Implement data-driven approaches to analyze screening outputs and guide iterative molecule design.
• Manage projects with CDMOs for research-grade synthesis and lead compound scale-up.
• Collaborate across disciplines to translate screening hits into validated chemical starting points for therapeutic programs.

Requirements

• Ph.D. in Chemistry, Chemical Engineering, or a related field.
• Must be based in or able to work onsite in Cambridge, MA, USA.
• ≥ 1 years of experience with automation, instrumentation, and integrating real-time analytics into experimental workflows.
• Strong background in organic synthesis, specifically designing and synthesizing novel organic compounds.
• Excellent problem-solving, communication, and collaboration skills.

Nice to have

• Familiarity with novel lipid design for drug delivery applications.
• Knowledge and implementation of biodegradability and tolerability design principles.
• Experience working in an autonomous or self-driving chemical lab environment.
• Hands-on experience with AI-driven experimental design or Bayesian optimization.
• Background in scaling workflows from proof-of-concept to routine high-throughput operation.

Culture & Benefits

• Competitive base compensation with bonus potential.
• Generous early-stage equity.
• Comprehensive U.S. and International benefits.
• Fast-paced startup environment guided by values of truth, trust, curiosity, grit, and velocity.
• Opportunity to work at the frontier of AI and physical sciences.