Research Associate

TL;DR

Research Associate (Vector Engineering): Assist with execution of in vitro and in vivo studies aimed at developing brain-wide gene therapy for neurodegenerative disease with an accent on molecular biology techniques and rodent handling. Focus on culturing stem cell-derived neurons, performing injections, tissue processing, staining, and microscopy analysis.

Location: On-Site in Cambridge, MA

Salary: $58,000/yr - $80,667/yr

Company

Fast-paced mission-driven collaborative laboratory developing next-generation AAV vectors for neuroscience research and CNS gene therapies.

What you will do

• Culture human embryonic stem cell-derived neurons
• Perform molecular biology techniques including DNA/RNA purification, PCR, qPCR, and protein analysis
• Conduct IP and IV injections in rodents, tissue sectioning, cryo-sectioning
• Execute immunohistochemistry staining and fluorescence microscopy
• Extract and purify RNA/DNA from mammalian tissues, organize and track samples
• Maintain records, analyze data, order supplies, troubleshoot, and present at team meetings

Requirements

• B.S. or M.S. in biology-related field
• Experience handling mice or small laboratory animals
• Hands-on experience extracting DNA/RNA from cells or tissues
• Foundational knowledge and hands-on experience with PCR and molecular biology techniques
• Hands-on experience with mammalian cell culture
• Experience in BL2 or BL2+ environment, exceptional organizational skills, strong communication

Culture & Benefits

• Comprehensive benefits including medical, dental, vision, life, disability insurance
• 401(k) retirement plan, flexible spending and health savings accounts
• At least 13 paid holidays, winter closure, paid time off, parental/family care leave
• Employee assistance program and other perks