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9 дней назад

Postdoctoral Associate (Virology/Functional Genomics)

70 000 - 92 666$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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TL;DR
Postdoctoral Associate (Virology/Functional Genomics): Investigating the host genetic landscape of HPV-driven cellular immortalization and transformation through CRISPRi/CRISPRa screens, hit validation, and mechanistic studies with an accent on host-pathogen interactions and virus-induced cancers. Focus on designing primary-cell experiments, completing sub-pool screens, analyzing screening data, and driving publications in collaboration with multiple institutes.

Location: Cambridge, MA, United States; full-time, 40 hours per week

Salary: $70,000.00–$92,666.67 per year

Company

hirify.global of MIT & Harvard conducts basic and translational biomedical research.

What you will do

  • Investigate the host genetic landscape of HPV-driven cellular immortalization and transformation.
  • Lead validation and mechanistic characterization of hits from genome-scale CRISPRi/CRISPRa screens.
  • Complete ongoing sub-pool screens and design and conduct experiments independently and with collaborators.
  • Develop and troubleshoot methods, maintain detailed experimental records, and share protocols.
  • Contribute to grants, scientific papers, and patents.

Requirements

  • PhD in virology, microbiology, genetics, immunology, or a closely related field.
  • Successful record of leading projects through scientific publications and conference presentations.
  • Hands-on expertise in functional genomics, including CRISPRi/CRISPRa screens, molecular cloning, lentivirus production, and next-generation sequencing.
  • Experience with virology assays and handling and modulating primary human cells with and without infection.
  • Training and expertise in virology and functional genomics are essential.
  • Excellent oral and written communication, wet-lab, organization, and time-management skills.
  • Ability to work independently and collaboratively, take initiative, learn new methods, and solve problems creatively.
  • Strong interest in host-pathogen interactions and virus-induced cancers.

Nice to have

  • Bioinformatic analysis of screening and sequencing data.

Culture & Benefits

  • Work in a multi-institute collaboration setting with opportunities to develop independent follow-up research directions.
  • Medical, dental, vision, life, and disability insurance.
  • 401(k), flexible spending and health savings accounts.
  • At least 13 paid holidays, winter closure, paid time off, parental and family care leave, and an employee assistance program.
  • Equal opportunity employer; reasonable accommodation is available for the application and interview process.

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