Research Associate – Expression (Biochemistry)

Location: San Francisco Bay Area, United States; onsite

Salary: $95K–$120K per year, plus equity

Company

hirify.global is a frontier research lab developing brain-computer interfaces that combine high-bandwidth neural interaction with advanced AI.

What you will do

• Design and execute assays to investigate how protein complexes assemble in a poorly understood biochemical system.
• Express and purify proteins, reconstitute complexes, and run mammalian cell-based assays to determine individual protein functions.
• Characterize protein variants and their effects on function to guide engineering efforts.
• Analyze and present findings, shape hypotheses, and design follow-up experiments with scientists.
• Maintain detailed experimental records and organized protein, plasmid, and cell inventories.

Requirements

• Bachelor’s or master’s degree in biochemistry, structural biology, or a related field.
• Experience with biochemical or biophysical methods for characterizing protein structure, dynamics, or protein-protein interactions.
• Hands-on experience with mammalian cell culture, transfection, and cell-based assays.
• Curiosity, attention to detail, and a systematic approach to troubleshooting.
• Strong documentation, communication, and collaboration skills.

Nice to have

• Experience expressing and purifying challenging proteins or protein complexes.
• Experience designing and implementing large-scale screens or high-throughput experiments.
• Experience with molecular biology techniques including cloning, mutagenesis, and plasmid preparation.

Culture & Benefits

• Full-time onsite work in the San Francisco Bay Area.
• Opportunity to take increasing ownership of experimental design and interpretation.
• Equity is offered.
• Applicants are encouraged to apply even if they do not meet every qualification; complementary strengths are valued when building the team.
• Equal opportunity employer committed to reasonable accommodations and a fair-chance hiring process.