Research Assistant III (Human Engineered Heart Tissue)

Location: Farmington, Connecticut, United States

Salary: $42,751–$71,575 per year; pay is determined by years of experience.

Company

hirify.global is an independent, nonprofit biomedical research institution focused on genetics, human disease, and genomic solutions for biomedical research.

What you will do

• Culture, differentiate, and quality-control iPSC lines from genetically diverse donors and generate iPSC-derived cardiomyocytes at scale.
• Fabricate 3D engineered heart tissues and microtissues in multiwell formats using standardized, reproducible protocols.
• Perform functional tissue assays measuring contractile force, kinetics, and calcium handling, including dose-response compound testing for drug safety and efficacy.
• Prepare samples for RNA-seq, single-cell assays, imaging, and other multi-omic profiling.
• Document experiments, metadata, line identifiers, and batch information; process data and apply quality-control criteria to support computational modeling.
• Support genome editing, in vivo mouse studies, laboratory operations, protocol maintenance, and training of new lab members.

Requirements

• Bachelor’s degree in biology, biomedical science, bioengineering, or a related field with 3+ years of relevant laboratory experience, or a Master’s degree with 1+ years of relevant experience.
• Hands-on mammalian cell culture experience; iPSC culture and differentiation experience is strongly preferred.
• Comfort with high-throughput, multiwell workflows and meticulous record keeping.
• Basic data analysis skills using Excel and Prism; R or Python is a plus.
• Strong organizational and communication skills, with the ability to work independently and collaboratively under tight timelines and defined deliverables.

Nice to have

• Experience with cardiomyocytes, tissue engineering, or physiological assays such as contractility and calcium imaging.
• Experience with pharmacology or compound screening.

Culture & Benefits

• Full-time work in a collaborative, milestone-driven research team combining stem cell biology, tissue engineering, cardiac physiology, genome editing, and multi-omics.
• Close collaboration with computational researchers developing digital twin models of the human heart.
• Work is based at hirify.global for Genomic Medicine and UConn Health in Farmington, Connecticut.
• hirify.global is an equal employment opportunity employer.