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13 дней назад

Postdoctoral Research Associate (Pharmacogenomics)

72 500$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Postdoctoral Research Associate (Pharmacogenomics): Investigating the genetic and molecular basis of variability in childhood cancer treatment response through multi-omics, computational analyses, and experimental functional validation with an accent on drug efficacy, treatment-related toxicity, and precision medicine. Focus on conducting functional genomics and single-cell studies, validating gene-drug interactions, and developing novel therapeutics for high-risk leukemias.

Location: Memphis, Tennessee, United States

Salary: Starting at $72,500 per year

Company

hirify.global is a pediatric research institution focused on childhood cancer and other catastrophic diseases, with a multidisciplinary pharmacogenomics program translating discoveries into precision pharmacotherapy.

What you will do

  • Lead an independent subproject investigating genetic and molecular mechanisms of variability in childhood cancer treatment response.
  • Integrate multi-omics and computational analyses with experimental functional validation for targeted agents and immunotherapeutics.
  • Define genetic and multi-omic mechanisms of anticancer drug efficacy and treatment-related toxicity using pediatric cancer and long-term survivor cohorts.
  • Use clinical-trial samples and single-cell approaches to study targeted-therapy response and immunotherapy resistance in childhood leukemia.
  • Conduct large-scale, high-throughput studies of gene-drug interactions using functional genomics and single-cell systems.
  • Apply chemical biology approaches, including molecular glues and proteolysis-targeting chimeras, to develop therapeutics for high-risk leukemias.

Requirements

  • PhD or equivalent doctoral degree in pharmacology, pharmaceutical sciences, genetics, molecular biology, or a related biomedical field, completed before the start date; candidates with a PharmD or MD and substantial research experience may also be considered.
  • Strong research productivity demonstrated through peer-reviewed publications.
  • Knowledge and research experience in at least one of pharmacology, human genetics, functional genomics, genome editing, or animal models.
  • Strong written and oral communication skills in English.
  • Ability to work independently and collaboratively in a multidisciplinary environment.

Nice to have

  • Experience with large-scale functional genomics studies, including in vitro or in vivo CRISPR screening.
  • Experience with high-throughput drug-sensitivity profiling or preclinical drug evaluation.
  • Research experience in cancer biology, cancer therapy, or treatment-related toxicity.

Culture & Benefits

  • Access to shared research resources, expert-led facilities, cutting-edge technology, and multidisciplinary collaboration.
  • Professional development through grant-writing workshops, individual development plans, teaching and mentoring opportunities, non-research career programs, and a professional-development allowance.
  • Competitive annual compensation, comprehensive benefits, and generous relocation assistance.
  • A supportive postdoctoral community focused on balance, connection, and inclusion.

Hiring process

  • Apply through the St. Jude careers portal.
  • Submit a cover letter describing research interests, technical background, career goals, and anticipated availability; a curriculum vitae with a complete publication list; a one- to two-page statement of research experience and interests; and contact information for three professional references.
  • Reference letters may be requested from shortlisted candidates; applications from search firms are not accepted.

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