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8 дней назад

Senior Scientist, Neuroimmunology, Biology-Discovery

119 100 - 187 500$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Senior Scientist, Neuroimmunology, Biology-Discovery (neuroimmunology and CNS drug discovery): Conducting in vitro and in vivo studies to generate mechanistic insights into microglial biology and support novel therapies for CNS diseases with an accent on preclinical models, immune-cell profiling, and translational biology. Focus on designing complex experiments, analyzing pharmacology and biomarker datasets, and providing data-driven recommendations for target validation and drug discovery programs.

Location: Boston, Massachusetts, United States; US and Puerto Rico residents only

Base salary: $119,100–$187,500 per year, plus annual bonus and long-term incentive eligibility where applicable.

Company

hirify.global develops pharmaceutical therapies and supports discovery and early development programs across neuroscience and other therapeutic areas.

What you will do

  • Conduct hands-on in vitro and in vivo procedures with downstream analyses.
  • Design and execute studies supporting pipeline programs, interpret complex datasets, and communicate findings to cross-functional teams.
  • Generate and interpret pharmacology, efficacy, biomarker, and mechanistic datasets for target validation and drug discovery.
  • Perform CNS immune-cell isolation, flow cytometry, immunophenotyping, molecular profiling, and histological analyses.
  • Collaborate across pharmacology, immunology, chemistry, biologics, biomarker sciences, and data science.
  • Provide scientific leadership and data-driven recommendations that influence program strategy and decisions.

Requirements

  • PhD in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field; postdoctoral industry experience is highly preferred. Alternatively, a master’s degree in one of these fields plus 8+ years of pharmaceutical or biotechnology industry experience.
  • Extensive hands-on experience with rodent in vivo studies.
  • Experience with mouse models of neurodegeneration, neuroinflammation, or CNS disease.
  • Expertise in flow cytometry, CNS immune-cell isolation, immunohistochemistry, and molecular biology techniques.
  • Proficiency with omics approaches, including RNA-seq and single-cell technologies, and data analysis.
  • Strong experimental design, statistical analysis, and problem-solving skills.
  • Excellent communication and collaboration skills in a cross-functional research environment.

Nice to have

  • Industry experience supporting discovery or early development programs in CNS disorders.
  • Experience with Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, or related neurodegenerative diseases.
  • Hands-on experience with transgenic rodent models, including behavioral, pharmacology, and biomarker studies.
  • Experience with primary microglia cultures, macrophages, immune-cell assays, or iPSC-derived CNS cell systems.
  • Familiarity with translational biomarkers, PK/PD relationships, and mechanism-based drug development.
  • Experience advancing programs from target validation through candidate selection and leading collaborative projects across multiple functions.

Culture & Benefits

  • Regular employee status with medical, dental, vision, insurance, retirement, and 401(k) benefits.
  • Paid holidays, vacation, compassionate leave, and sick days.
  • Relocation support listed as domestic/international; visa sponsorship available.
  • Laboratory-based position with no travel required; flexible work arrangements are not applicable.
  • Work involves OEB4, BSL2, and standard laboratory reagents.

Hiring process

  • Applications are accepted for the Boston, Massachusetts position from US and Puerto Rico residents.
  • Accommodation support is available during the hiring process upon request.

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