Scientist 3, Lung Biology & Inflammation (Immunology)

Location: South San Francisco, California, United States; hybrid schedule with 3 days per week on campus. No relocation benefits are available.

Salary: $103,400.00–$192,000.00 USD annually, based on the primary California location; discretionary annual bonus may be available.

Company

hirify.global develops medicines and conducts research addressing complex health challenges, including serious and life-threatening diseases.

What you will do

• Lead projects investigating cellular and molecular mechanisms of lung injury, chronic inflammation, and tissue repair.
• Advance research-stage programs into early clinical development by generating robust proof-of-concept data.
• Use in vitro and in vivo models to evaluate novel molecules and targeted delivery systems.
• Dissect inflammatory lung disease pathogenesis and identify mechanisms of action for breakthrough therapies.
• Drive pipeline research, explore new biological pathways for target discovery, and collaborate across immunology, human genetics, biomarker discovery, and early clinical development.
• Present research findings at intra- and inter-departmental scientific meetings.

Requirements

• PhD in immunology, stem cell biology, molecular biology, biochemistry, or a related field, with a demonstrated record of high-quality publications.
• Deep understanding of lung biology, particularly chronic respiratory diseases, tissue remodeling or regeneration, or host-microbe interactions.
• Hands-on molecular biology expertise, including cellular transfections, gene expression profiling, precision genome editing, and targeted RNA delivery technologies.
• Hands-on experience isolating primary cells from human or mouse tissues, conducting in vitro immunological assays, and using multi-dimensional flow cytometry.
• Track record of independently designing, executing, troubleshooting, and interpreting complex experiments leading to first-author publications in top-tier journals.

Nice to have

• Experience with complex in vitro systems, including airway or alveolar organoids, air-liquid interface 3D cultures, or organ-on-a-chip technologies.
• Experience with targeted therapeutic delivery of nucleic acid modalities such as mRNA, siRNA, or ASOs using viral or non-viral vectors.
• Experience with computational data analysis, including scRNA-seq, spatial transcriptomics, or mining public or clinical datasets.

Culture & Benefits

• Inclusive, integrity-focused, and creative work environment.
• Benefits are available for the position.
• Discretionary annual bonus may be available based on individual and company performance.
• Equal opportunity employment and disability accommodations are provided.