Senior HEOR Scientist

Location: Full-time remote-eligible; candidates must be based in the United States. Primary location: South San Francisco, California.

Salary: $156,200–$290,200 annually, based on the primary South San Francisco location.

Company

hirify.global develops medicines and invests in research and development for serious and life-threatening diseases.

What you will do

• Lead the design, execution, interpretation, and dissemination of retrospective observational studies and end-to-end real-world evidence generation.
• Analyze insurance claims, electronic medical records, and patient registry data; develop research protocols and statistical analysis plans.
• Apply causal inference, propensity score matching, regression modeling, and other advanced analytical methods.
• Design and maintain reusable codebases, libraries, and web applications using R, Python, SQL, and related tools.
• Modernize analytics through automation, workflow improvements, and responsible ML/AI methodologies.
• Provide technical expertise, code reviews, quality assurance, and mentorship across internal and external initiatives.

Requirements

• Bachelor’s degree with 5+ years of relevant applied analytics or economic modeling experience, or a Master’s degree or PhD in a quantitative or health-related discipline with 3+ years of relevant experience.
• Experience designing and conducting observational research and real-world evidence analytics using claims, EHR, or patient registry datasets.
• Advanced proficiency developing high-quality, reproducible deliverables with R, Python, or SQL.
• Strong foundation in observational study design, advanced statistical methods, and quantitative data validation.
• Ability to work autonomously with minimal supervision, manage multiple concurrent deliverables, and maintain rigorous scientific attention to detail.
• Exceptional written and verbal communication skills, including the ability to explain technical methodologies and complex findings to non-technical stakeholders.

Nice to have

• Experience translating strategic business needs into analytical designs and technical solutions with cross-functional stakeholders.
• Familiarity with scalable analytics, including cloud, containers, workflow orchestration, CI/CD, and QA automation, and/or responsible ML/AI use.
• Experience with economic modeling in Excel, VBA, or R, including documentation and sensitivity analysis.
• Publication or external communication experience, such as posters, manuscripts, or methods talks, and/or contributions to internal communities of practice.

Culture & Benefits

• Full-time regular employment with a remote-eligible arrangement for candidates throughout the United States.
• Annual discretionary bonus may be available based on individual and company performance.
• Benefits are provided as detailed in the linked benefits information.
• Relocation benefits are not approved for this posting.
• Equal employment opportunity and applicant accommodation support are provided.