Senior Scientist, Virus Construction (Oncolytic Viruses)

Location: Milton Park, United Kingdom; 5-day on-site expectation.

Company

hirify.global develops oncolytic immunotherapies based on an HSV-1 platform to induce local and systemic anti-tumor responses.

What you will do

• Design, construct, test, and characterize novel HSV-derived oncolytic virus candidates in accordance with regulatory requirements.
• Introduce, evaluate, qualify, execute, and transfer virus characterization methods to other departments.
• Produce cell banks, virus controls, and other biological materials, including non-GMP virus material for internal studies and external collaborations.
• Support translational, clinical, and non-clinical studies through virus provision, technical input, data analysis, and reporting.
• Contribute technical input to BLA, IND, and IMPD submissions and information requests.
• Manage daily Virus Construction operations, biological safety, documentation, equipment, and consumables.

Requirements

• B.A. or B.Sc. degree in a relevant biological science.
• 6–8+ years of industry experience, preferably in a Cell & Gene Therapy or virology-based environment covering the product lifecycle from concept to commercialization.
• Significant experience in molecular construction and characterization of novel ATMPs or gene therapies.
• Experience with molecular biology and cloning, cell culture, cell-based analytical methods, ELISA, PCR/qPCR, virus particle characterization, immunoblotting, whole-genome sequencing, or related techniques.
• Project, line, and time management skills; ability to work independently, in a small team, and cross-functionally with effective verbal and written communication.
• Ability to perform independent statistical data analysis and good IT skills in Microsoft Word, Excel, Outlook, and core applications.

Nice to have

• M.S., Ph.D., or other postgraduate degree in biochemistry, virology, or a related science.

Culture & Benefits

• Work in a purpose-driven environment focused on transforming cancer treatment and improving patient outcomes.
• Collaborate across Analytical Development, Translational Research, Process Development, Quality Assurance, Regulatory Affairs, and external partners.
• Work on-site at Milton Park, typically five days per week.
• Operate according to health, biological safety, equipment, and company policy requirements.