Senior Bioinformatics Scientist (Cancer Genomics)

Location: US Remote

Salary: $117,400–$146,800 USD per year

Company

hirify.global develops cell-free DNA testing and personalized genetic diagnostics for oncology, women’s health, and organ health.

What you will do

• Design, develop, and validate algorithms and statistical models that extract insights from large-scale genomic datasets for early cancer detection.
• Architect, implement, and deploy automated clinical-diagnostics workflows for variant calling, fusion detection, and quality control.
• Analyze complex multi-omic data using high-performance internal pipelines.
• Optimize computational infrastructure through code reviews, technical documentation, and continuous improvement.
• Collaborate with wet-lab scientists and statisticians on cross-departmental research initiatives and milestones.

Requirements

• Ph.D. in Bioinformatics, Computer Science, Statistics, Cancer Biology, or a related quantitative field.
• 0–3 years of professional or postgraduate experience in bioinformatics or computational biology.
• Strong communication skills and the ability to present complex computational findings to cross-functional stakeholders.
• Deep expertise in high-throughput DNA sequencing analysis, including sequence alignment, mapping, and clinical-grade variant calling.
• Track record of developing high-impact bioinformatics methodologies.
• Advanced knowledge of data structures, algorithm design, and computational complexity analysis.
• High proficiency in Python, NumPy, Pandas, and Scikit-learn for data manipulation and automation.
• Experience with workflow orchestration languages, with WDL preferred, for building and versioning scalable bioinformatics pipelines.
• Experience with cloud-based distributed computing environments, specifically AWS.
• Familiarity with analytical techniques and biomarkers in cancer biology.
• Working knowledge of public genomic databases including TCGA, COSMIC, or OncoKB.
• Proficiency in Linux, command-line tools, and shell scripting.

Culture & Benefits

• Collaborative work with statisticians, geneticists, doctors, laboratory scientists, software engineers, and other specialists.
• Medical, dental, vision, life, and disability benefits for eligible employees and dependents.
• Free testing for employees and immediate family members, plus fertility care benefits.
• Pregnancy and baby bonding leave, 401(k) benefits, commuter benefits, and an employee referral program.
• Inclusive workplace committed to diverse backgrounds, experiences, abilities, and perspectives.