Senior Manager, DNA Manufacturing Operations & Integration (Biotech)

Location: Norwood, Massachusetts, United States; 70% in-office work model with flexibility to support critical manufacturing activities, technology transfers, regulatory inspections, and significant operational events.

Salary: $130,800–$209,400 per year, plus potential annual discretionary bonus, incentive compensation, or equity award.

Company

hirify.global develops mRNA medicines and operates a biopharmaceutical manufacturing platform focused on transforming medicine.

What you will do

• Lead, develop, and coach Specialists and Senior Specialists across DNA and Cell Bank manufacturing processes.
• Own the DNA Manufacturing continuous improvement and Operational Excellence program, including opportunity prioritization, execution, and benefits realization.
• Lead complex cross-functional initiatives, manufacturing change controls, technology transfers, manufacturing readiness, and project execution.
• Use operational data, performance indicators, dashboards, and trend analysis to identify risks, capacity constraints, improvement opportunities, and priorities.
• Provide GMP manufacturing and quality-system leadership for investigations, risk assessments, change implementation, inspection readiness, and regulatory activities.
• Partner with MSAT, Quality Assurance, Supply Chain, Digital, CMC Development, Planning, and other stakeholders to improve manufacturing execution and explore Generative AI and advanced digital tools.

Requirements

• Bachelor's degree in engineering, science, manufacturing, or another relevant technical discipline, or an equivalent combination of education and relevant industry experience.
• Demonstrated experience in biopharmaceutical manufacturing, technical operations, manufacturing sciences, operational excellence, or a related environment.
• Experience leading and developing people, including setting priorities, coaching performance, creating clarity, and building organizational capability.
• Experience influencing and leading within a complex matrix organization, including stakeholders outside direct authority.
• Proven ownership and successful execution of complex cross-functional projects or programs from problem definition and strategy through implementation and sustained results.
• Experience with GMP manufacturing and quality systems, including change control and mechanisms for implementing and sustaining changes in a regulated environment.
• Experience supporting technology transfer, manufacturing readiness, process implementation, or other cross-functional technical programs.
• Strong understanding of continuous improvement and Operational Excellence principles, with the ability to translate them into measurable manufacturing performance improvements.
• Ability to use data, trends, and performance indicators to identify problems, establish priorities, and drive decisions and improvement; strong communication, stakeholder management, and organizational leadership skills.
• Ability to operate effectively in ambiguity, connect technical and business considerations, and take ownership of cross-functional problems.

Nice to have

• Experience supporting regulatory inspections and inspection readiness activities.

Culture & Benefits

• In-person collaboration supported through a 70/30 in-office work model.
• Healthcare and voluntary benefit programs, plus fitness, mindfulness, and mental health support.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Paid time off including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
• Savings and investment programs, location-specific perks, and a smoke-free, alcohol-free, and drug-free workplace.