Senior Scientist, Translational Immunology

Location: Cambridge, Massachusetts, United States; 100% onsite.

Salary: $130,800–$209,400 per year, with potential discretionary bonus, incentive compensation, or equity award.

Company

hirify.global develops mRNA technology, medicines, vaccines, and therapeutics.

What you will do

• Lead translational immunology strategy for assigned infectious disease programs and identify evidence needed for candidate selection, study design, and development decisions.
• Design and lead studies using human samples and preclinical models to characterize immune-cell responses and connect cellular, antibody, and functional findings to program questions.
• Develop fit-for-purpose assays, establish controls, provide scientific oversight, and interpret the limits of experimental results.
• Collaborate across virology, bacteriology, antigen design, clinical development, medical affairs, biomarkers, and computational sciences.
• Set scientific priorities, communicate rationale and uncertainty to research and development leaders, and evaluate emerging methods for platform and discovery studies.
• Mentor scientists and research associates and help build capabilities in experimental design and data interpretation.

Requirements

• PhD in immunology or a related discipline, with a strong foundation in immune-cell biology and relevant research experience.
• At least 2 years of experience.
• Deep expertise in at least one area of cellular immunology, including B-cell, T-cell, or innate immune-cell biology, with hands-on experience studying primary immune cells.
• Experience designing and interpreting cellular assays, including multiparameter flow cytometry and functional assays relevant to the area of expertise.
• Ability to translate a biological or clinical question into a study plan and use findings to guide research or development decisions.
• Experience leading scientific work across disciplines, mentoring colleagues, and clearly communicating complex results and limitations.
• Ability to learn new biological areas and methods quickly, adapt to changing program needs, and contribute beyond the primary specialty.

Nice to have

• B-cell and antibody biology, including antigen-specific cell isolation, antibody discovery, repertoire analysis, epitope mapping, or antibody binding and function.
• T-cell biology, including antigen-specific responses, differentiation and memory, antigen presentation, or functional assessment.
• Innate immune-cell biology, including myeloid-cell function, immune activation, or mechanisms shaping vaccine responses.
• Mucosal or tissue immunity, including local immune responses and relevant human or preclinical models.
• Single-cell or other high-dimensional immune profiling, integrating cellular, molecular, and functional data.
• Infectious disease, vaccine, or therapeutic development experience, including translational studies using human samples.

Culture & Benefits

• 100% onsite work supporting real-time collaboration, direct mentorship, and site-based operations.
• Smoke-free, alcohol-free, and drug-free work environment.
• Healthcare coverage and voluntary benefit programs.
• Fitness, mindfulness, mental health, family planning, fertility, adoption, and surrogacy support.
• Paid time off including vacation, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
• Savings and investment programs plus location-specific perks.