Staff / Principal Security Engineer, AI Safety and Security

Location: Cambridge, MA, USA; London, UK; San Francisco, CA, USA; other location: Alewife, Cambridge, MA, and Europe

Expected base salary: $192,000–$306,000 USD annually for U.S.-based positions. International salaries are set to the local market.

Company

hirify.global builds AI systems that combine advanced models with scientific tools and automated laboratories to accelerate discovery in medicine, materials, and energy.

What you will do

• Threat-model AI models, deployed services, scientific workflows, and other consequential systems.
• Investigate architectures, code, configurations, and operational evidence; run adversarial tests and build prototypes to identify weaknesses.
• Define security requirements and assess protections for models, sensitive data, research assets, and supporting systems.
• Combine model evaluations and security-testing results into evidence-based recommendations and deployment conditions.
• Work with Security, Safety, and engineering owners to prioritize improvements, define acceptance criteria, and verify outcomes.
• Develop reusable threat models, assessment methods, and technical guidance for future systems.

Requirements

• Substantial hands-on security experience with deep expertise in security architecture, application or infrastructure security, offensive security, incident response, or a related discipline.
• Experience resolving consequential security problems across multiple teams, from investigation through validation.
• Strong technical judgment and the ability to examine unfamiliar systems, code, configurations, and security claims.
• Curiosity about AI safety and scientific systems, with the ability to learn unfamiliar domains and reason with incomplete evidence.
• Clear technical writing, collaboration, and communication skills.

Nice to have

• Experience securing ML infrastructure, model assets, research environments, or AI agents.
• Experience evaluating safeguards, adversarial robustness, or defenses against sophisticated threats.
• Experience translating risk assessments into technical requirements, assurance evidence, or deployment decisions.
• Experience in scientific environments where digital access can have significant real-world consequences.

Culture & Benefits

• Startup-speed environment focused on AI for scientific discovery.
• Competitive base compensation, bonus potential, and early-stage equity.
• Full-time U.S. employees receive medical, dental, and vision coverage, life and disability insurance, flexible time off, holidays, parental leave, educational assistance, commuter benefits, and subsidized lunch.
• Full-time employees outside the U.S. receive benefits tailored to their region.
• Work guided by values of truth, trust, curiosity, grit, and velocity.