2 дня назад
Senior Scientist or Scientist - Drug Metabolism and Pharmacokinetics (DMPK)
104 000 - 186 160$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Scientist or Scientist - Drug Metabolism and Pharmacokinetics (DMPK) (DMPK): Conducting hands-on bioanalytical, in vitro DMPK, and in vivo pharmacokinetic studies to support small-molecule drug discovery and development with an accent on LC-MS/MS analysis, ADME assays, and preclinical formulations. Focus on designing experiments, executing dosing and tissue-sampling protocols, interpreting PK/PD data, and communicating findings in an academic research environment.
Location: Memphis, TN, United States
Salary: $104,000–$186,160 per year for the Senior Scientist or Scientist role. The Scientist range is $86,320–$154,960; the Senior Scientist range is $104,000–$186,160.
Company
is an academically oriented, nonprofit research institution supporting drug discovery and development.
What you will do
- Design and execute laboratory studies supporting small-molecule drug discovery and development.
- Perform quantitative LC-MS/MS bioanalysis of small and large molecules in plasma, tissues, and other biological matrices.
- Run in vitro DMPK and ADME assays, including protein binding, microsomal stability, hepatocyte metabolism, and cell-monolayer permeability.
- Conduct in vivo PK studies, including dosing, blood sampling, and organ or tissue collection.
- Prepare preclinical formulations and analyze, document, and communicate study results.
Requirements
- Bachelor's degree in Chemistry, Biology, Pharmacology, Pharmaceutical Sciences, or a related discipline.
- Demonstrated LC-MS/MS bioanalysis experience with small molecules.
- Hands-on experience with in vitro DMPK/ADME assays and in vivo PK studies.
- Working knowledge of preclinical solution and suspension formulation techniques.
- Strong attention to detail, organizational skills, independent planning, and effective collaboration.
- Scientist: 8 years of relevant experience, or 6 years with a master's degree, or 3 years with a PhD. Senior Scientist: 10 years, or 8 years with a master's degree, or 5 years with a PhD.
Culture & Benefits
- Bench-focused laboratory work in an academic, nonprofit environment.
- Direct experimental execution is emphasized over managing or outsourcing studies.
- Regular and predictable attendance is required.
- Benefits are available through .
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