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2 дня назад

Senior Scientist or Scientist - Drug Metabolism and Pharmacokinetics (DMPK)

104 000 - 186 160$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Senior Scientist or Scientist - Drug Metabolism and Pharmacokinetics (DMPK) (DMPK): Conducting hands-on bioanalytical, in vitro DMPK, and in vivo pharmacokinetic studies to support small-molecule drug discovery and development with an accent on LC-MS/MS analysis, ADME assays, and preclinical formulations. Focus on designing experiments, executing dosing and tissue-sampling protocols, interpreting PK/PD data, and communicating findings in an academic research environment.

Location: Memphis, TN, United States

Salary: $104,000–$186,160 per year for the Senior Scientist or Scientist role. The Scientist range is $86,320–$154,960; the Senior Scientist range is $104,000–$186,160.

Company

hirify.global is an academically oriented, nonprofit research institution supporting drug discovery and development.

What you will do

  • Design and execute laboratory studies supporting small-molecule drug discovery and development.
  • Perform quantitative LC-MS/MS bioanalysis of small and large molecules in plasma, tissues, and other biological matrices.
  • Run in vitro DMPK and ADME assays, including protein binding, microsomal stability, hepatocyte metabolism, and cell-monolayer permeability.
  • Conduct in vivo PK studies, including dosing, blood sampling, and organ or tissue collection.
  • Prepare preclinical formulations and analyze, document, and communicate study results.

Requirements

  • Bachelor's degree in Chemistry, Biology, Pharmacology, Pharmaceutical Sciences, or a related discipline.
  • Demonstrated LC-MS/MS bioanalysis experience with small molecules.
  • Hands-on experience with in vitro DMPK/ADME assays and in vivo PK studies.
  • Working knowledge of preclinical solution and suspension formulation techniques.
  • Strong attention to detail, organizational skills, independent planning, and effective collaboration.
  • Scientist: 8 years of relevant experience, or 6 years with a master's degree, or 3 years with a PhD. Senior Scientist: 10 years, or 8 years with a master's degree, or 5 years with a PhD.

Culture & Benefits

  • Bench-focused laboratory work in an academic, nonprofit environment.
  • Direct experimental execution is emphasized over managing or outsourcing studies.
  • Regular and predictable attendance is required.
  • Benefits are available through hirify.global.

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