Principal Scientist - Materials Science

Location: United States - Connecticut - Groton; on-premise work

Annual base salary: $106,000–$176,600, plus a 15% bonus target and eligibility for a share-based long-term incentive program.

Company

hirify.global develops medicines and vaccines by applying advanced science and technologies across research and development.

What you will do

• Lead materials science activities across multidisciplinary projects from discovery through drug product launch.
• Define solid forms of active pharmaceutical ingredients, including salts, polymorphs, hydrates, solvates, and co-crystals.
• Characterize particle and solid-state properties using spectroscopy, X-ray diffraction, microscopy, thermal analysis, and related techniques.
• Integrate physical and surface characterization data into formulation and drug product process development.
• Apply computational approaches to design experiments and predict pharmaceutical material properties and performance.
• Oversee external laboratory partners, mentor scientists, support regulatory submissions and patents, and develop new scientific approaches.

Requirements

• Ph.D. in Chemistry, Engineering, Materials Science, Pharmaceutics, or a related field with at least 5 years of relevant industry experience, or a relevant Master’s degree with at least 10 years of experience.
• Experience with small-molecule crystallization and solid-state characterization, including X-ray powder diffraction, spectroscopy, microscopy, laser diffraction, calorimetry, thermogravimetric analysis, or NMR.
• Experience preparing regulatory submissions and query responses related to solid forms and particle characterization.
• Strong data analysis, statistical, communication, collaboration, and leadership skills.
• Permanent authorization to work in the United States is required; U.S. work visa sponsorship is not available.

Nice to have

• Experience using computational tools such as HABIT, Materials Studio, Mercury, CosmoTherm, or SimCU to predict pharmaceutical material properties.
• Experience curating data for predictive tools and characterizing fine powders and surface properties.
• Knowledge of the physical and chemical properties required for drug substance and drug product intermediate manufacturing and formulation.

Culture & Benefits

• Collaborative work with multidisciplinary project teams and academic partners.
• Opportunities to coach colleagues and lead scientific approaches within the global Materials Science organization.
• Relocation support may be available based on business needs and eligibility.
• Benefits include 401(k) matching and retirement contributions, paid vacation and leave, and medical, prescription, dental, and vision coverage.