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13 дней назад

Postdoctoral Fellow, PD and Rare Disease

80 000$
Формат работы
onsite
Тип работы
fulltime
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Postdoctoral Fellow, PD and Rare Disease (Cell Biology/Biotech): Investigating lysosomal dysfunction, Parkinson’s disease risk variants, and alpha-synuclein clearance across disease-relevant CNS cell types with an accent on cellular assays, live-cell imaging, and quantitative image analysis. Focus on designing activity-based probe assays, analyzing lysosomal and lipid homeostasis, and collaborating across a multi-institutional research network.

Location: South San Francisco, United States

Salary: $80,000 per year

Company

hirify.global is a biotechnology company developing biotherapeutics that cross the blood-brain barrier through its TransportVehicle platform for neurodegenerative and lysosomal storage diseases.

What you will do

  • Investigate cellular mechanisms of lysosomal dysfunction associated with Parkinson’s disease.
  • Study how lysosomal Parkinson’s disease risk variants affect lysosomal function, lipid homeostasis, and alpha-synuclein clearance across CNS cell types.
  • Design and implement cellular assays to evaluate lysosomal function and identify novel regulators using activity-based probes.
  • Analyze experimental data, interpret results, and communicate findings clearly.
  • Collaborate with human genetics, functional genomics, and academic research partners across a multi-institutional network.
  • Attend conferences and publish research in peer-reviewed journals.

Requirements

  • Ph.D. in Cell Biology, Biochemistry, Neuroscience, or a related field.
  • 0–2 years of related experience.
  • Expertise in live-cell imaging and quantitative image analysis.
  • Proficiency in mammalian cell culture and transfection, western blotting, immunofluorescence, and other biochemical and cellular techniques.
  • Strong analytical, critical-thinking, organizational, oral, and written communication skills.
  • Creative, responsible, and collaborative approach to research.

Nice to have

  • Experience with membrane trafficking or lysosomal biology.
  • Experience with iPSC-derived CNS models.

Culture & Benefits

  • Full-time research position in a dynamic and collaborative environment.
  • Collaboration with ASAP-affiliated laboratories and access to shared resources and complementary expertise.
  • Opportunities to attend conferences and publish in peer-reviewed journals.
  • 401(k), healthcare coverage, employee stock purchase plan, and additional benefits.
  • Commitment to a diverse and inclusive workplace.

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