Clinical Pharmacology Lead (MIDD)

Location: Cambridge, Massachusetts, United States. Hybrid role requiring residence within commuting distance and on-site work an average of 2.5 days per week or more as needed. Permanent U.S. work authorization is required; visa sponsorship is not available.

Salary: $106,000–$176,600 annual base salary, plus a 15% bonus target and eligibility for a share-based long-term incentive program.

Company

hirify.global is a pharmaceutical company developing medicines through clinical research, model-informed drug development, and cross-functional scientific collaboration.

What you will do

• Represent Clinical Pharmacology on clinical subteams, development teams, and other multifunctional project teams.
• Lead clinical pharmacology expertise, deliverables, and best practices across assigned Internal Medicine projects.
• Design and execute clinical pharmacology plans, including PK/PD analyses, immunogenicity and biomarker strategies, and clinical development plans.
• Plan and oversee study-level activities such as protocol authoring, clinical phase oversight, reporting, and dose-range finding.
• Develop and implement end-to-end MIDD plans using innovative analytical methods to optimize doses, dosage regimens, and study designs.
• Contribute to regulatory documents and interactions, and represent the organization through publications, presentations, scientific societies, and industry consortia.

Requirements

• Strong quantitative skills and expertise in mechanistic PK/PD modeling, systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations.
• Experience with tools such as NONMEM and R.
• M.D./Ph.D. or equivalent training and experience in pharmacokinetics, pharmacometrics, clinical pharmacology, engineering, or a related discipline; 0+ years of industry experience accepted.
• Pharm.D. or equivalent training and experience in a related discipline, with 2+ years of industry experience.
• Excellent written and verbal communication, presentation skills, and the ability to influence and collaborate across disciplines.
• Ability to work in global team meetings across different time zones and maintain permanent U.S. work authorization.

Culture & Benefits

• Collaborative, multifunctional environment focused on innovative clinical pharmacology and MIDD methods.
• Opportunities for learning, professional growth, scientific publications, presentations, and external representation.
• 401(k) plan with hirify.global matching contributions and an additional retirement savings contribution.
• Paid vacation, holidays, personal days, caregiver/parental leave, and medical leave.
• Medical, prescription drug, dental, and vision coverage.