Scientist, In Vivo Process Development Downstream (Lentivirus)

Location: Philadelphia, Pennsylvania, United States

Salary: $133,195–$172,370 per year, plus potential annual bonus, stock-based incentives, paid time off, and benefits.

Company

hirify.global develops cancer immunotherapies, including CAR T-cell and T-cell receptor engineered cell therapies.

What you will do

• Design and optimize scalable, safe, and cost-effective downstream processes for Lentivirus manufacturing.
• Develop technical solutions using advanced chemistry, biochemistry, engineering, statistical, and modelling principles.
• Support manufacturing activities, process scale-up, and optimization of large-biomolecule processes.
• Manage day-to-day laboratory operations, documentation, data analysis, and safety compliance.
• Prepare technical reports and presentations while collaborating with multidisciplinary groups.
• Train, guide, mentor, and technically support colleagues in process execution and troubleshooting.

Requirements

• BS with 6+ years of relevant post-graduate experience, MS with 4+ years, or PhD/PharmD in science, engineering, bioprocessing, or biotechnology.
• Hands-on proficiency with downstream unit operations for large biomolecules, including chromatography and filtration.
• Understanding of bioprocess scale-up principles and cGMP practices.
• Proficiency with Microsoft Word, Excel, PowerPoint, and data analysis tools such as JMP or GraphPad.
• Strong collaboration, communication, organization, problem-solving, and attention-to-detail skills.
• Onsite work in Philadelphia, Pennsylvania, United States is required.

Nice to have

• Experience developing viral vector processes.
• Experience using Design of Experiments for process development.
• Experience with fermentation, cell culture, large-biomolecule analysis, or large-scale bioprocessing in GMP or non-GMP settings.
• Mentorship and team leadership experience.

Culture & Benefits

• Full-time employment within a cancer-immunotherapy organization.
• Medical, dental, vision, and life insurance plans.
• Paid time off and potential annual bonus and stock-based long-term incentives.
• Inclusive work environment focused on collaboration, development, and employee empowerment.