5 дней назад
Sr Scientist (Mass Spectrometry-Based Proteomics)
127 122 - 171 988$
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Описание вакансии
Текст:
TL;DR
Sr Scientist (Mass Spectrometry-Based Proteomics): Developing high-throughput mass spectrometry-based proteomics workflows and screening platforms for target identification and drug discovery with an accent on automated sample preparation, LC-MS/MS analysis, and quantitative proteomics. Focus on optimizing next-generation screening platforms, analyzing high-dimensional data, and generating insights into mechanism of action, target engagement, and selectivity.
Location: Thousand Oaks, California, United States
Salary: $127,121.75–$171,988.25 annually
Company
is a biotechnology company developing medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.
What you will do
- Design, develop, and optimize high-throughput mass spectrometry-based proteomics workflows and screening platforms for drug discovery.
- Execute automated sample preparation and LC-MS/MS analyses across multiple high-throughput proteomics assays.
- Operate and troubleshoot advanced mass spectrometry systems, including platforms such as Orbitrap Astral.
- Collaborate with chemistry, biology, and disease-area teams as a technical and scientific subject matter expert.
- Analyze proteomics data to assess mechanism of action, target engagement, and selectivity.
- Present research findings and maintain accurate documentation of experiments, protocols, and analyses.
Requirements
- PhD, PharmD, or MD with relevant experience; or a master’s degree with 4 years of directly related experience; or a bachelor’s degree with 6 years of directly related experience.
- Experience developing mass spectrometry-based proteomics assays and analyzing proteomics data.
- Experience operating advanced mass spectrometry platforms and working with sample preparation miniaturization and automation.
- Strong quantitative and computational skills for high-dimensional proteomics data analysis.
- Excellent organizational, verbal, and written communication skills, with a record of producing reliable and reproducible results.
Nice to have
- Doctorate in proteomics, chemoproteomics, biochemistry, chemistry, or a related discipline.
- Three or more years of experience in the biotechnology or pharmaceutical industry.
- Knowledge of targeted protein degradation or E3 ligase biology.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Annual bonus program and stock-based long-term incentives.
- Paid time off, work-life balance support, and career development opportunities.
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