Senior Engineer I, Process Engineering (mRNA/LNP)

Location: Norwood, Massachusetts, United States. Only individuals who qualify as U.S. persons are eligible; non-U.S. persons cannot be sponsored for an export control license.

Salary: $109,200–$174,600 per year, with potential eligibility for a discretionary bonus, incentive compensation, or equity award.

Company

hirify.global develops mRNA technology platforms and medicines for clinical and commercial use.

What you will do

• Provide technical subject matter expertise for drug substance processes including IVT, chromatography, TFF, lipid mixing, and LNP formulation.
• Design, scale up, and implement modular and small-scale process skids in accordance with GxP requirements and global engineering standards.
• Develop PFDs, P&IDs, URS, and FRS documentation for drug substance manufacturing systems.
• Design and optimize CIP systems, equipment specifications, and automation strategies with internal stakeholders and vendors.
• Support root cause investigations, deviation analysis, continuous improvement, technical reviews, and standardization initiatives.
• Maintain audit readiness, documentation, and training requirements while mentoring junior engineers.

Requirements

• Bachelor’s degree in Chemical Engineering, Biochemical Engineering, or a related field; a master’s degree is preferred.
• 7–10 years of experience in process engineering or manufacturing science within biopharmaceutical, biotechnology, or sterile manufacturing environments.
• Hands-on experience with IVT, chromatography, TFF, and LNP drug substance processes.
• Experience designing processes and specifying equipment in regulated manufacturing environments.
• Experience with process simulation and modeling, including mass and energy balances, scale-up modeling, and dynamic or steady-state simulation.
• Must qualify as a U.S. person under U.S. export control laws; visa sponsorship for non-U.S. persons is unavailable.

Nice to have

• Experience with bioprocess skid design, automation, and process analytical technologies.
• Experience leading cross-functional technical projects or supporting personalized medicine and individualized manufacturing.
• Training in GxP/GMP compliance and knowledge of FDA, EMA, and ICH regulations.

Culture & Benefits

• Healthcare coverage and voluntary benefits programs.
• Fitness, mindfulness, and mental health resources.
• Family planning support, including fertility, adoption, and surrogacy benefits.
• Paid vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
• Savings and investment programs, plus location-specific benefits.