6 дней назад
Scientist II, Radiopharmacology
90 000 - 110 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist II, Radiopharmacology (Radiochemistry/Radiopharmacology): Developing and evaluating radiolabeled compounds for diagnostic and therapeutic applications with an accent on radiolabeling reactions, conjugation chemistry, analytical quality control, and in vivo studies. Focus on optimizing radiochemical protocols, interpreting biodistribution and dosimetry data, ensuring radiation safety, and supporting cross-functional study execution.
Location: Onsite in Rockville, Maryland, United States
Salary: $90,000–$110,000 per year
Company
develops and supports oncology research involving radiopharmacology, radiochemistry, molecular imaging, and targeted radionuclide applications.
What you will do
- Design and execute radiolabeling reactions using diagnostic and therapeutic isotopes, including Lu-177, Ac-225, In-111, Zr-89, At-211, I-131, and Pb-212.
- Perform conjugation reactions involving bifunctional chelators, peptides, proteins, antibodies, and other biological molecules.
- Develop, optimize, and troubleshoot radiochemical synthesis, radiolabeling, formulation, and analytical protocols.
- Conduct quality control and stability testing using TLC, radio-TLC, column chromatography, HPLC, and radio-HPLC.
- Support in vivo studies and analyze biodistribution, pharmacokinetic, imaging, dosimetry, and therapeutic data.
- Prepare technical documentation, maintain laboratory records, train junior staff, and collaborate with scientific, project management, and laboratory operations teams.
Requirements
- PhD in radiochemistry, chemistry, biochemistry, pharmaceutical sciences, radiopharmaceutical sciences, or a related field.
- Expertise in radiochemistry, radiopharmacology, radiobiology, molecular imaging, and diagnostic or therapeutic radionuclides.
- Practical experience with radiolabeling chemistry, bifunctional chelators, conjugation chemistry, and radiopharmaceutical formulation.
- Experience analyzing in vivo data from radiolabeled compounds, including biodistribution, pharmacokinetics, imaging, or dosimetry.
- Knowledge of radiation safety and the handling, storage, use, and disposal of radioactive materials.
- Ability to manage multiple priorities, document work accurately, troubleshoot experiments, and collaborate in a multidisciplinary laboratory environment.
Nice to have
- Experience with preclinical biodistribution, pharmacokinetic, imaging, dosimetry, or therapeutic studies.
Culture & Benefits
- Full-time laboratory position in a multi-level facility.
- Work includes collaboration across scientific and operational teams.
- Regular exposure to chemical hazards, radioactive materials, blood, body fluids, and tissue.
- Physical requirements include lifting and moving packages weighing up to 50 pounds and performing repetitive laboratory movements.
- Commitment to an inclusive work environment.
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