Forward-Deployed Biostatistics Subject Matter Expert (AI)

Location: Remote within the U.S. only; ideally Boston, New York City, or San Francisco, with 20–40% domestic travel

Salary: $180,000–$250,000 per year plus equity

Company

Builds and deploys AI scientist agents to accelerate scientific research and the development of new medicines.

What you will do

• Improve LLM agents' ability to execute complex statistical analysis and clinical trial design tasks in scientific and customer data environments.
• Design benchmarks, acceptance criteria, and failure-mode evaluations for SAP development, sample size determination, and endpoint analysis.
• Partner with biostatisticians and clinical development leaders to apply AI agents to statistical and regulatory deliverables.
• Evaluate AI-generated outputs for statistical accuracy and regulatory soundness, identifying issues that require further investigation.
• Support engagement scoping, success metrics, and pre-sales technical evaluations with go-to-market and account teams.
• Build trusted relationships with customer biostatisticians and research leaders.

Requirements

• 5+ years of biostatistical experience in biotech or pharma, including sponsor or CRO experience.
• Graduate degree in Statistics, Biostatistics, or a related discipline; a Ph.D. is preferred.
• Expertise in SAP development, sample size determination, and early-phase I/II clinical trial design.
• Proficiency in R and/or SAS, with experience in statistical programming and validation.
• Familiarity with ICH and FDA standards, CSRs, IND filings, and CDISC-compliant SDTM and ADaM datasets.
• Ability to work remotely from the U.S. and travel domestically 20–40% of the time.

Nice to have

• Experience in oncology, immuno-oncology, immunology, cardiovascular, neurology, or hepatology/MASH.
• Proficiency in Python and/or TypeScript/JavaScript.
• Experience rapidly prototyping, working independently, and delivering complex tasks in high-stakes environments.
• Experience working across diverse projects in sprint-based formats and reproducing or QCing statistical analyses.

Culture & Benefits

• Mission-driven, fast-moving environment with opportunities to work across complex scientific and AI projects.
• Full healthcare coverage with premiums paid for employees and dependents.
• Paid parental leave, family-growth support, fertility coverage, and mental health support.
• 401(k) matching, quarterly health and wellness benefits, commuter benefits, and pet-care support.
• Daily office meals, dinners when working late, regular team off-sites, and company events.