Scientist - Rare Disease Biology

Location: South San Francisco, California, United States; onsite scientific research role

Salary: $123,052.80–$166,483.20 annually

Company

hirify.global is a biotechnology company developing medicines for serious illnesses across oncology, inflammation, general medicine, rare disease, and obesity-related conditions.

What you will do

• Design, execute, analyze, and interpret in vitro and ex vivo studies of rare disease mechanisms and therapeutic hypotheses.
• Investigate Thyroid Eye Disease biology, including immune dysregulation, fibroblast activation, inflammatory signaling, extracellular matrix regulation, and tissue remodeling.
• Generate reproducible data supporting target identification, validation, and progression of rare disease programs.
• Integrate experimental findings with scientific literature, human genetics, clinical observations, and multi-omic datasets.
• Collaborate with disease biologists, computational scientists, translational researchers, academic investigators, foundations, and CROs.
• Present scientific findings and recommendations to project teams, governance forums, and departmental audiences while maintaining accurate documentation.

Requirements

• Doctorate degree, or a master’s degree plus 2 years of relevant scientific research experience, or a bachelor’s degree plus 4 years of relevant scientific research experience.
• Expertise in fibroblast or stromal cell biology, tissue remodeling, fibrosis, extracellular matrix biology, inflammation, or fibro-inflammatory disease.
• Experience with cell-based, molecular, and biochemical assays and advanced in vitro or ex vivo disease models, including primary human cells, tissue-derived cultures, or organoids.
• Strong quantitative and data-analysis skills, including interpretation of complex biological datasets and integration of experimental, genetic, omics, clinical, and literature data.
• Ability to work effectively in collaborative, multidisciplinary, matrixed research environments and communicate complex scientific concepts clearly.
• Familiarity with AI-enabled scientific tools, computational workflows, image analysis, automation, or advanced data analytics is desirable.

Culture & Benefits

• Collaborative, innovative, science-based research environment focused on serving patients.
• Health, dental, vision, life, disability, and flexible spending benefits for eligible employees and dependents.
• Retirement and savings plan with company contributions, stock-based long-term incentives, and an annual bonus program.
• Paid time-off plans, work-life balance support, and career development opportunities.
• Flexible work models may be available where applicable; the listed role is located in South San Francisco.

Hiring process

• Sponsorship for this role is not guaranteed.
• Applications are anticipated to be accepted until September 16, 2026, with possible extension if additional candidates are needed.