Early Development Program Lead – Cambridge (Biotechnology)

Location: Fully remote; can be performed from anywhere. Occasional domestic and international travel of approximately 10% is expected for team meetings and events.

Company

hirify.global is a global biopharmaceutical company developing therapies for patients with serious and rare diseases, including small molecule and oligonucleotide therapeutics.

What you will do

• Lead early-stage drug development programs from late lead optimization through IND and first-in-human development.
• Coordinate cross-functional teams across medicinal chemistry, CMC, formulation, biology, toxicology, DMPK/ADME, translational science, regulatory, clinical, and patient advocacy.
• Define scientific strategies, early Target Product Profiles, project objectives, integrated plans, budgets, timelines, and risk registers.
• Integrate multidisciplinary data to support candidate selection and facilitate decisions across competing priorities.
• Manage CRO and CDMO relationships and oversee outsourced activities.
• Prepare program documents and updates for senior leadership, governance committees, and regulatory discussions.

Requirements

• PhD in Medicinal Chemistry, Pharmacology, Pharmaceutical Sciences, Translational Medicine, Biochemistry, or a related discipline relevant to small molecule or oligonucleotide drug discovery and development.
• 15+ years of pharmaceutical or biotechnology industry experience, including increasing responsibility.
• 5+ years of industry experience in small molecule drug and/or oligonucleotide therapeutic discovery and development.
• Experience leading cross-functional drug development matrix teams and advancing programs from lead optimization through IND and into first-in-human development.
• Experience engaging with FDA and EMA in early development settings, including pre-IND, INTERACT, and Type B/C meetings.
• Strong communication, influencing, alignment, and complex decision-making skills in a matrix environment.

Culture & Benefits

• Flexible work schedules with purposeful in-person collaboration.
• Competitive retirement benefits, global equity awards, and participation in the Employee Stock Purchase Plan.
• Career development through internal learning programs, external programs, LinkedIn Learning, and role-specific training.
• AI-powered and on-demand learning tools, including a digital assistant for internal resources.
• Technology and IT support for collaboration across locations and time zones, plus global recognition programs and Employee Resource Groups.