Process Development Senior Scientist (Drug Product Technologies)

Location: Thousand Oaks, California, United States

Salary: $126,066.05–$170,559.95 annual salary

Company

hirify.global is a biotechnology company developing and manufacturing medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.

What you will do

• Plan, lead, and execute formulation, stability, process development, and fill/finish studies for early-stage biologic drug product programs.
• Develop and characterize liquid and lyophilized formulations for ADCs, oligonucleotides, monoclonal antibodies, multispecifics, and other complex modalities.
• Integrate formulation, analytical, stability, process, manufacturability, and regulatory data to guide product and development strategies.
• Investigate critical quality attributes, degradation pathways, aggregation, fragmentation, charge and size variants, particles, surface interactions, and modality-specific attributes.
• Apply high-throughput tools, AI/ML, automation, and data science to formulation screening, predictive modeling, workflow acceleration, and decision-making.
• Provide scientific leadership, mentor junior scientists, author technical and regulatory documents, and support technology transfer and manufacturing troubleshooting with internal and external partners.

Requirements

• Doctorate degree, or a master's degree with 2 years of scientific experience, or a bachelor's degree with 4 years of scientific experience.
• PhD in Pharmaceutics, Biotechnology, Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or a related field with 3+ years of relevant industry experience preferred.
• Experience in biologics drug product formulation, stability assessment, process development, and/or fill/finish operations.
• Knowledge of biologics and complex modality development, including formulation stability, degradation pathways, aggregation, particulates, manufacturability, comparability, and control strategies.
• Experience with analytical and biophysical techniques such as UPLC/HPLC, SEC, IEX, RP-HPLC, HIC, CE-SDS, LC-MS, subvisible particle analysis, viscosity, osmolality, and stability-indicating methods.
• Experience with technical reports, regulatory submissions, clinical-stage development, technology transfer, and risk-based decision-making.

Nice to have

• Direct experience with ADCs, oligonucleotides such as siRNAs, or other complex biologic modalities.
• Experience with linker-payload stability, drug-to-antibody ratio, free payload impurities, ADC quality attributes, and oligonucleotide degradation or formulation stability.
• Experience applying AI/ML, LLMs, in silico tools, automation, or data science to R&D workflows.

Culture & Benefits

• Collaborative, innovative, and science-based work environment.
• Health, dental, vision, life, disability, and flexible spending benefits.
• Retirement and savings plan with company contributions.
• Discretionary annual bonus and stock-based long-term incentives.
• Paid time off and career development opportunities.

Hiring process

• Applications are accepted until a sufficient number of candidates is received or a candidate is selected.
• Sponsorship for the role is not guaranteed.