6 дней назад
Lead Scientist, Purification Development (Protein Purification)
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Lead Scientist, Purification Development (Protein Purification): Developing and characterizing downstream manufacturing processes for recombinant therapeutic proteins with an accent on protein purification, chromatography, process characterization, and viral clearance. Focus on leading scale-down studies, interpreting DoE and risk-assessment results, supporting manufacturing and regulatory submissions, and providing technical leadership across multiple projects.
Location: Tuas, Singapore
Company
is a global life sciences company developing and manufacturing therapies for clients worldwide.
What you will do
- Lead process development, process characterization, and viral clearance activities, including study planning, technical supervision, and interpretation of results.
- Conduct risk assessments, scale-down model qualification, Design of Experiments, resin lifetime studies, and regulatory submission support.
- Lead purification activities using affinity, mixed-mode, and ion-exchange chromatography with ÄKTA/UNICORN systems, as well as UF/DF and viral reduction studies.
- Train and mentor junior scientists and new hires in purification technologies and laboratory techniques.
- Prepare and review protocols, reports, SOPs, and technical documentation while supporting manufacturing, troubleshooting, and technology transfer.
- Represent projects in internal and external customer communications and coordinate multiple projects for timely delivery.
Requirements
- Degree or PhD in Life Sciences or a related field with relevant industry experience.
- 4–7 years of experience in protein purification or process development; PhD candidates with 2–5 years of experience may be considered.
- Strong expertise in protein purification and process characterization.
- Experience with statistical software such as JMP for DoE data analysis is highly advantageous.
- Understanding of cGMP and BLA requirements, with strong technical writing, communication, problem-solving, and analytical skills.
- Ability to work collaboratively across projects and provide scientific leadership.
Culture & Benefits
- Agile working culture in a global life sciences organization.
- Inclusive and ethical workplace focused on diversity and integrity.
- Professional growth through cross-functional projects and global exposure.
- Comprehensive medical insurance with optional partially subsidized family coverage.
- Company transport from designated MRT locations to and from the Tuas site.
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