LC-MS/MS Sr. Scientist (ADME/DMPK)

Location: St. Charles, Missouri, USA; candidates must be within a commutable distance. Full-time laboratory role with Sunday–Thursday or Saturday–Wednesday schedules, 8:00 AM–5:00 PM.

Company

hirify.global provides analytical testing, contract research, pharmaceutical, environmental, food, and life sciences services through a global laboratory network.

What you will do

• Develop LC-MS methods for ADME/DMPK applications and new assay development.
• Conduct production assays across ADME Toxicology Services and support additional discovery service areas as needed.
• Troubleshoot and maintain mass spectrometers and HPLC equipment, including Sciex or Waters instruments.
• Manage laboratory inventories, reagents, buffers, equipment, and data management systems.
• Review and QC data and reports while maintaining high data quality, reproducibility, and accurate documentation.
• Lead client projects, support validation and R&D programs, train colleagues, and communicate project updates to internal and external clients.

Requirements

• Bachelor’s degree plus at least 5 years of industry laboratory experience with LC-MS/MS; or a master’s degree plus 3 years; or a Ph.D. plus 1 year.
• Direct LC-MS or LC-UV experience in ADME/DMPK applications within a contract research organization or industry laboratory.
• Expertise in mass spectrometry-based quantification for ADME/DMPK applications in biological matrices and analytical method development.
• Experience with quality management systems, bioanalytical method validation concepts, FDA and ICH guidelines, liquid handling, automation, SPE, HTS, and large-scale screening.
• Experience leading small teams, managing projects, and delivering R&D or innovation programs.
• Authorization to work indefinitely in the United States without restriction or sponsorship is required.

Culture & Benefits

• Full-time employment with medical, dental, and vision coverage.
• Life and disability insurance.
• 401(k) plan with company match.
• Paid vacation and holidays.
• Work in a collaborative laboratory environment focused on drug discovery, quality, safety, and advancing human health.