Scientist, Cheminformatics (AI/ML)

Location: Emeryville, California, United States; onsite

Salary: $150,000–$190,000 annual, depending on experience

Company

hirify.global is a clinical-stage drug discovery company developing therapeutics for protein misfolding diseases, rare diseases, and oncology through its Navigator platform combining high-throughput synthetic biology, generative chemistry, and AI/ML.

What you will do

• Partner with analytical chemists and biologists to develop high-throughput ADMET assays and assess data quality.
• Design experiments and analyses for robust, quantitative DMPK measurements across hundreds of thousands of compounds.
• Guide compound and building-block selection for high-throughput synthesis, ADMET assays, and OpenADMET competitions.
• Build data and computational infrastructure for processing and analyzing assay results at scale.
• Translate OpenADMET capabilities into platform tools for drug discovery teams and help prioritize assay development.
• Collaborate with machine learning scientists, software engineers, biologists, chemists, and automation engineers.

Requirements

• PhD in Chemistry, Cheminformatics, Chemical Biology, Computational Chemistry, or a related discipline.
• 3–5 years of research experience; industry experience is preferred, with strong recent PhD graduates also considered.
• Expertise in organic or medicinal chemistry, ideally including DMPK, with the ability to reason about structure–property relationships.
• Practical analytical chemistry knowledge, especially HPLC, SFC, and LC-MS, including retention behavior and artifact identification.
• Strong statistics and data science fundamentals, including experimental design, batch effects, uncertainty, and large-dataset analysis.
• Fluency in Python and/or R and standard cheminformatics tools such as RDKit and pandas, with experience writing reproducible analyses.

Nice to have

• Industry drug discovery experience.
• Experience working with OpenADMET or other open-science projects.
• A public paper, preprint, or software repository demonstrating relevant work.

Culture & Benefits

• Multidisciplinary, collaborative work across chemistry, biology, machine learning, software, and automation.
• Opportunity to contribute to public-facing open science through OpenADMET.
• Health benefits including medical, dental, and vision coverage.
• Equity and 401(k) matching.
• Inclusive and supportive environment that values nontraditional backgrounds.