23 часа назад
Head of Regeneron Cell Medicines
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Head of Regeneron Cell Medicines (Cell Therapy/CAR T): Defining strategy and leading discovery-to-early-clinical development for ex vivo and in vivo cell medicines, with an accent on CAR T engineering, delivery technologies, and chemo-free conditioning. Focus on advancing programs to IND and Phase I, solving biodistribution and safety challenges, and building multidisciplinary scientific organizations.
Location: On-site 4+ days per week in Cambridge, Massachusetts, with regular travel to Tarrytown, New York, and Seattle, Washington.
Company
is a biopharmaceutical company developing innovative medicines and cell-based therapies.
What you will do
- Define the scientific vision, portfolio strategy, and platform investments for ex vivo and in vivo cell medicines.
- Lead cross-functional programs from target validation through IND preparation, Phase I manufacturing, and early clinical readouts.
- Advance CAR T design, in vivo delivery using viral vectors and LNPs, tissue and cell targeting, potency, and manufacturing strategies.
- Guide technical problem-solving across biodistribution, pharmacokinetics, on/off-target effects, immunogenicity, and safety risk mitigation.
- Build and mentor a high-performing organization of senior scientific leaders and functional experts across multiple sites.
- Manage external collaborations, budgets, headcount, resource allocation, compliance, and executive governance communications.
Requirements
- Advanced degree such as PhD, MD, or MD/PhD in cell biology, immunology, bioengineering, or a related discipline.
- 20+ years of biopharmaceutical R&D experience, including substantial cell-based therapy experience and programs advanced from discovery to IND and early clinical development.
- Demonstrated leadership of multidisciplinary, multisite teams and senior scientific leaders.
- Deep expertise in cell engineering, CAR design, viral vectors, potency and identity assays, process and analytical development, and translational biology.
- Experience with in vivo gene delivery, biodistribution and pharmacokinetics, on/off-target risk assessment, immunogenicity, CMC, regulatory pathways, and nonclinical safety packages.
- Strong portfolio management, financial planning, executive communication, stakeholder management, and talent development skills.
Culture & Benefits
- Scientific culture focused on rigor, innovation, accountability, collaboration, and inclusion.
- Commitment to talent development, coaching, succession planning, and performance management.
- Competitive total rewards package that may include bonuses, equity, retirement benefits, 401(k) matching, insurance, paid time off, and family support benefits.
- On-site collaboration is emphasized for many roles.
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