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19 часов назад

Scientist Antibody Discovery

86 320 - 154 960$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Scientist Antibody Discovery (antibody discovery and biologics): Leading the discovery of biologics against targets relevant to the St. Jude pediatric population using display methods and B-cell screening with an accent on high-diversity library construction, repertoire analysis, and affinity maturation. Focus on integrating molecular biology, antibody characterization, lab automation, bioinformatics, and advanced methods such as 10x Genomics and cryo-EM epitope analysis.

Location: Memphis, Tennessee, United States

Salary: $86,320–$154,960 per year

Company

hirify.global conducts pediatric biomedical research and provides specialized care focused on preventing children from dying at the dawn of life.

What you will do

  • Lead the discovery of biologics against targets relevant to the St. Jude pediatric population.
  • Apply phage, yeast, and mammalian display methods for lead discovery and affinity maturation.
  • Build high-diversity libraries from synthetic and animal repertoires.
  • Analyze antibody repertoires and perform B-cell screening from immunized or synthetic repertoires.
  • Develop high-throughput molecular biology workflows for construct and library generation.

Requirements

  • Bachelor's degree in a relevant scientific area.
  • Eight years of relevant work experience, or six years with a Master's degree, or three years with a PhD.
  • Experience with B-cell technologies and 10x Genomics for sequence discovery.
  • Experience with antibody characterization techniques, including FACS, BLI, and epitope binning.
  • Experience with antibody-related bioinformatics or software packages.

Nice to have

  • Experience integrating machine-learning approaches with display methods.
  • Experience combining cryo-EM techniques with epitope analysis of antibody repertoires.
  • Experience using lab automation to support antibody discovery.

Culture & Benefits

  • Full-time employment within the Antibody Discovery Collaborative Centre.
  • Collaboration with researchers in the Department of Host Microbe Interactions.
  • Benefits are available through hirify.global.

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