19 часов назад
Scientist Antibody Discovery
86 320 - 154 960$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Scientist Antibody Discovery (antibody discovery and biologics): Leading the discovery of biologics against targets relevant to the St. Jude pediatric population using display methods and B-cell screening with an accent on high-diversity library construction, repertoire analysis, and affinity maturation. Focus on integrating molecular biology, antibody characterization, lab automation, bioinformatics, and advanced methods such as 10x Genomics and cryo-EM epitope analysis.
Location: Memphis, Tennessee, United States
Salary: $86,320–$154,960 per year
Company
conducts pediatric biomedical research and provides specialized care focused on preventing children from dying at the dawn of life.
What you will do
- Lead the discovery of biologics against targets relevant to the St. Jude pediatric population.
- Apply phage, yeast, and mammalian display methods for lead discovery and affinity maturation.
- Build high-diversity libraries from synthetic and animal repertoires.
- Analyze antibody repertoires and perform B-cell screening from immunized or synthetic repertoires.
- Develop high-throughput molecular biology workflows for construct and library generation.
Requirements
- Bachelor's degree in a relevant scientific area.
- Eight years of relevant work experience, or six years with a Master's degree, or three years with a PhD.
- Experience with B-cell technologies and 10x Genomics for sequence discovery.
- Experience with antibody characterization techniques, including FACS, BLI, and epitope binning.
- Experience with antibody-related bioinformatics or software packages.
Nice to have
- Experience integrating machine-learning approaches with display methods.
- Experience combining cryo-EM techniques with epitope analysis of antibody repertoires.
- Experience using lab automation to support antibody discovery.
Culture & Benefits
- Full-time employment within the Antibody Discovery Collaborative Centre.
- Collaboration with researchers in the Department of Host Microbe Interactions.
- Benefits are available through .
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