Senior Scientist, Biologics Design and Function (Biologics)

Location: Onsite in Spring House, Pennsylvania, United States

Company

Johnson & Johnson develops healthcare solutions and medicines through its Innovative Medicine and MedTech businesses.

What you will do

• Design, implement, and interpret mechanistic and functional studies supporting biologic molecule design, therapeutic differentiation, and discovery decisions.
• Apply immunological and biological expertise as a subject matter expert guiding molecule optimization.
• Develop innovative cellular assays, experimental approaches, and technologies to clarify therapeutic mechanisms and biological function.
• Evaluate emerging technologies and accelerate biologics functional assay workflows.
• Translate mechanistic insights into actionable therapeutic strategies while solving complex biological problems.
• Communicate scientific findings through presentations, technical reports, patent applications, publications, and project-team discussions.

Requirements

• Master’s degree or higher in Immunology, Cell Biology, Biochemistry, Bioengineering, or a related scientific field; a PhD is highly preferred.
• At least 4 years of industry experience with a Master’s degree or at least 2 years with a PhD.
• Deep understanding of immunology, disease biology, and immune cell signaling, activation, differentiation, and functional responses.
• Experience advancing biologic therapeutics and discovery programs in complex research environments.
• Expertise in designing, developing, and interpreting mechanistic cellular assays using primary human innate and adaptive immune cells.
• Ability to influence multidisciplinary teams and communicate effectively in matrixed organizations.

Nice to have

• Experience with multispecific antibodies, immune-engaging therapeutics, or other complex biologic modalities.
• Success developing innovative technologies or discovery platforms.
• Strong publication, patent, or therapeutic candidate advancement record.
• Hands-on experience with high-throughput binding and functional assays, including reporter assays, MSD, Incucyte, xCELLigence, or flow cytometry.

Culture & Benefits

• Collaborative, multidisciplinary research environment focused on scientific excellence and innovation.
• Opportunities to contribute directly to discovery programs and strategic initiatives.
• Development of scientific leadership capabilities through multidisciplinary project teams.
• Inclusive workplace with an emphasis on continuous learning and equal opportunity.