Scientist I Analytical Chemist (LC-MS)

Location: St. Charles, Missouri, United States. On-site laboratory role requiring a commutable distance. Full-time schedule: Sunday–Thursday or Saturday–Wednesday, 8:00 PM–5:00 AM.

Company

hirify.global provides analytical testing and contract research services across food, environmental, pharmaceutical, cosmetic, genomics, and life sciences markets.

What you will do

• Conduct production assays primarily for ADME Toxicology Services and support other discovery service areas as needed.
• Develop and optimize LC-MS methods for ADME/DMPK applications and new assay development.
• Troubleshoot and maintain mass spectrometers and HPLC equipment while managing laboratory reagents, buffers, and inventory.
• Support method validation, data and report quality control, data management systems, and service-line expansion.
• Lead client projects with minimal supervision, communicate project updates, and provide cross-functional support.
• Train colleagues and external users while contributing to research and development objectives.

Requirements

• Bachelor’s degree with at least 5 years of relevant laboratory experience, master’s degree with at least 3 years, Ph.D. with at least 1 year, or equivalent education and experience.
• Direct LC-MS or LC-UV experience in ADME/DMPK applications within a CRO or industry laboratory.
• Experience with analytical method development and optimization, mass spectrometry-based quantification in biological matrices, and quality management systems.
• Knowledge of bioanalytical method validation under FDA and ICH guidelines, plus experience with liquid handling, automation, SPE, HTS, and large-scale screening.
• Experience leading small teams, managing projects, and delivering R&D or innovation programs.
• Must be authorized to work indefinitely in the United States without restriction or sponsorship.

Nice to have

• Experience with Sciex or Waters instrumentation.
• Interest in drug discovery and advancing human health.

Culture & Benefits

• Collaborative laboratory environment with opportunities to support cross-functional teams.
• Comprehensive medical, dental, and vision coverage.
• Life and disability insurance.
• 401(k) plan with company match.
• Paid vacation and holidays.