Scientist, Process Development (mRNA)

Location: Waltham, Massachusetts, United States

Salary: $105,000–$145,000 per year

Company

hirify.global is a technology-driven biotechnology company developing advanced therapies through integrated technologies, end-to-end services, and manufacturing expertise.

What you will do

• Lead development, optimization, and scale-up experiments for mRNA production processes.
• Characterize mRNA samples using electrophoresis, spectrophotometry, and HPLC/UPLC.
• Collaborate with MSAT, analytical development, and external clients on mRNA therapeutic projects.
• Support business development by preparing statements of work and proposals for external clients.
• Communicate experimental results and project progress to internal and external stakeholders.
• Contribute to SOPs and technical documentation.

Requirements

• BS or MS in Microbiology, Bioengineering, Biochemistry, or a related discipline, with 8+ years of relevant experience.
• At least 4 years of experience working with mRNA-based therapeutics.
• Hands-on experience with in-vitro transcription, plasmid DNA linearization, mRNA processing, TFF, and chromatography.
• Experience operating ÄKTA Avant/Pure chromatography systems and Repligen KrosFlow Kr2i filtration skids.
• Strong understanding of tech transfer for mRNA drug substance production and process scaling from bench scale to GMP manufacturing.
• Work location: Waltham, Massachusetts, United States.

Nice to have

• Experience with mRNA-LNP formulation and mixing technologies or equipment.
• Experience using JMP for Design of Experiments and data analysis.
• Familiarity with GMP regulations, Quality by Design principles, and regulatory filing documentation.

Culture & Benefits

• Regular employment with hirify.global.
• Equal employment opportunity and reasonable accommodations for qualified individuals with disabilities.